Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YoeB-RelB |
Location | 1861304..1861809 | Replicon | chromosome |
Accession | NZ_CP071881 | ||
Organism | Mucilaginibacter rubeus strain P2-0.1 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | J3L22_RS08165 | Protein ID | WP_090532546.1 |
Coordinates | 1861555..1861809 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | J3L22_RS08160 | Protein ID | WP_090532548.1 |
Coordinates | 1861304..1861558 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
J3L22_RS33640 | 1857364..1857819 | + | 456 | WP_243770649.1 | hypothetical protein | - |
J3L22_RS33645 | 1857879..1857926 | + | 48 | Protein_1601 | hypothetical protein | - |
J3L22_RS33650 | 1857996..1858133 | + | 138 | WP_243770648.1 | hypothetical protein | - |
J3L22_RS08155 (J3L22_08155) | 1858349..1861195 | + | 2847 | WP_112655611.1 | excinuclease ABC subunit UvrA | - |
J3L22_RS08160 (J3L22_08160) | 1861304..1861558 | + | 255 | WP_090532548.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
J3L22_RS08165 (J3L22_08165) | 1861555..1861809 | + | 255 | WP_090532546.1 | Txe/YoeB family addiction module toxin | Toxin |
J3L22_RS08170 (J3L22_08170) | 1861855..1863642 | + | 1788 | WP_112655609.1 | DUF885 domain-containing protein | - |
J3L22_RS08175 (J3L22_08175) | 1863778..1864662 | - | 885 | WP_112655608.1 | UbiA family prenyltransferase | - |
J3L22_RS08180 (J3L22_08180) | 1864793..1865320 | + | 528 | WP_112655606.1 | YceI family protein | - |
J3L22_RS08185 (J3L22_08185) | 1865339..1866448 | + | 1110 | WP_112655604.1 | type III polyketide synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10205.76 Da Isoelectric Point: 9.3469
>T197115 WP_090532546.1 NZ_CP071881:1861555-1861809 [Mucilaginibacter rubeus]
VKIIFQNPAWEDYLYWQTTDKSILKKINSLIKEIERTPYEGSGKPEPLKHNLAGWWSRRINLEHRLIYRVEADAIFILQC
RYHY
VKIIFQNPAWEDYLYWQTTDKSILKKINSLIKEIERTPYEGSGKPEPLKHNLAGWWSRRINLEHRLIYRVEADAIFILQC
RYHY
Download Length: 255 bp
>T197115 NZ_CP095726:193683-194030 [Listeria innocua]
CTGATGGTGAAGCGTGGTGACGTTTACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATAAGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATCGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CGAAGTTGCCAACACATGTGGAAGCTACTCGTAAAGACGGCTTTGAAAGAGATTCTGTCATTCTATTAGAACAAATTAGA
ACGATAGATAAACAACGCCTGACAGATAAGATTACACATTTGGACGAGGAACTAATGGCCAAGGTAAATCAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTTTAA
CTGATGGTGAAGCGTGGTGACGTTTACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATAAGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATCGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CGAAGTTGCCAACACATGTGGAAGCTACTCGTAAAGACGGCTTTGAAAGAGATTCTGTCATTCTATTAGAACAAATTAGA
ACGATAGATAAACAACGCCTGACAGATAAGATTACACATTTGGACGAGGAACTAATGGCCAAGGTAAATCAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTTTAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9776.16 Da Isoelectric Point: 5.7377
>AT197115 WP_090532548.1 NZ_CP071881:1861304-1861558 [Mucilaginibacter rubeus]
MEITTYTAFRQQLKSFLDKVRNDHKPLVVTSANAEDIVVISKADYESMEETFYLLKSPKNAERLLHGIQEYEKGLGKERK
LLEE
MEITTYTAFRQQLKSFLDKVRNDHKPLVVTSANAEDIVVISKADYESMEETFYLLKSPKNAERLLHGIQEYEKGLGKERK
LLEE
Download Length: 255 bp
>AT197115 NZ_CP095726:193401-193679 [Listeria innocua]
GTGTTAGAGAAAGAAAAACGGACGATAATATCCGTAGAACTGACACAGGAAATGGTACAAGAACTCGACGTAGTTGTAGA
AAAAGAAAAAATGGGGCGGAGTGAAGTTATAATGGAAGCAACGCAACAATTTTTACAGGAGAAAAGAGCTCGTGAATTAA
GAGACGAGATGGAACGCGGCTATGCAGAAATGGCGACGATTAATTTCGCCATTGCGTGCGAGTGTACTCATGTCGAAGCA
GAGGCAGAAGACAGGAATATTAGTATTTTAGGAGGTTAA
GTGTTAGAGAAAGAAAAACGGACGATAATATCCGTAGAACTGACACAGGAAATGGTACAAGAACTCGACGTAGTTGTAGA
AAAAGAAAAAATGGGGCGGAGTGAAGTTATAATGGAAGCAACGCAACAATTTTTACAGGAGAAAAGAGCTCGTGAATTAA
GAGACGAGATGGAACGCGGCTATGCAGAAATGGCGACGATTAATTTCGCCATTGCGTGCGAGTGTACTCATGTCGAAGCA
GAGGCAGAAGACAGGAATATTAGTATTTTAGGAGGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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