Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1861304..1861809 Replicon chromosome
Accession NZ_CP071881
Organism Mucilaginibacter rubeus strain P2-0.1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3L22_RS08165 Protein ID WP_090532546.1
Coordinates 1861555..1861809 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3L22_RS08160 Protein ID WP_090532548.1
Coordinates 1861304..1861558 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3L22_RS33640 1857364..1857819 + 456 WP_243770649.1 hypothetical protein -
J3L22_RS33645 1857879..1857926 + 48 Protein_1601 hypothetical protein -
J3L22_RS33650 1857996..1858133 + 138 WP_243770648.1 hypothetical protein -
J3L22_RS08155 (J3L22_08155) 1858349..1861195 + 2847 WP_112655611.1 excinuclease ABC subunit UvrA -
J3L22_RS08160 (J3L22_08160) 1861304..1861558 + 255 WP_090532548.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J3L22_RS08165 (J3L22_08165) 1861555..1861809 + 255 WP_090532546.1 Txe/YoeB family addiction module toxin Toxin
J3L22_RS08170 (J3L22_08170) 1861855..1863642 + 1788 WP_112655609.1 DUF885 domain-containing protein -
J3L22_RS08175 (J3L22_08175) 1863778..1864662 - 885 WP_112655608.1 UbiA family prenyltransferase -
J3L22_RS08180 (J3L22_08180) 1864793..1865320 + 528 WP_112655606.1 YceI family protein -
J3L22_RS08185 (J3L22_08185) 1865339..1866448 + 1110 WP_112655604.1 type III polyketide synthase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-84)

Antitoxin

(1-72)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10205.76 Da        Isoelectric Point: 9.3469

>T197115 WP_090532546.1 NZ_CP071881:1861555-1861809 [Mucilaginibacter rubeus]
VKIIFQNPAWEDYLYWQTTDKSILKKINSLIKEIERTPYEGSGKPEPLKHNLAGWWSRRINLEHRLIYRVEADAIFILQC
RYHY

Download         Length: 255 bp

>T197115 NZ_CP095726:193683-194030 [Listeria innocua]
CTGATGGTGAAGCGTGGTGACGTTTACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATAAGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATCGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CGAAGTTGCCAACACATGTGGAAGCTACTCGTAAAGACGGCTTTGAAAGAGATTCTGTCATTCTATTAGAACAAATTAGA
ACGATAGATAAACAACGCCTGACAGATAAGATTACACATTTGGACGAGGAACTAATGGCCAAGGTAAATCAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9776.16 Da        Isoelectric Point: 5.7377

>AT197115 WP_090532548.1 NZ_CP071881:1861304-1861558 [Mucilaginibacter rubeus]
MEITTYTAFRQQLKSFLDKVRNDHKPLVVTSANAEDIVVISKADYESMEETFYLLKSPKNAERLLHGIQEYEKGLGKERK
LLEE

Download         Length: 255 bp

>AT197115 NZ_CP095726:193401-193679 [Listeria innocua]
GTGTTAGAGAAAGAAAAACGGACGATAATATCCGTAGAACTGACACAGGAAATGGTACAAGAACTCGACGTAGTTGTAGA
AAAAGAAAAAATGGGGCGGAGTGAAGTTATAATGGAAGCAACGCAACAATTTTTACAGGAGAAAAGAGCTCGTGAATTAA
GAGACGAGATGGAACGCGGCTATGCAGAAATGGCGACGATTAATTTCGCCATTGCGTGCGAGTGTACTCATGTCGAAGCA
GAGGCAGAAGACAGGAATATTAGTATTTTAGGAGGTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References