Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 76072..76577 Replicon chromosome
Accession NZ_CP071880
Organism Mucilaginibacter rubeus strain P2-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3L21_RS00420 Protein ID WP_090532546.1
Coordinates 76072..76326 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3L21_RS00425 Protein ID WP_090532548.1
Coordinates 76323..76577 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3L21_RS00400 (J3L21_00400) 71433..72542 - 1110 WP_112655604.1 type III polyketide synthase -
J3L21_RS00405 (J3L21_00405) 72561..73088 - 528 WP_112655606.1 YceI family protein -
J3L21_RS00410 (J3L21_00410) 73219..74103 + 885 WP_112655608.1 UbiA family prenyltransferase -
J3L21_RS00415 (J3L21_00415) 74239..76026 - 1788 WP_112655609.1 DUF885 domain-containing protein -
J3L21_RS00420 (J3L21_00420) 76072..76326 - 255 WP_090532546.1 Txe/YoeB family addiction module toxin Toxin
J3L21_RS00425 (J3L21_00425) 76323..76577 - 255 WP_090532548.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J3L21_RS00430 (J3L21_00430) 76686..79532 - 2847 WP_112655611.1 excinuclease ABC subunit UvrA -
J3L21_RS33640 79748..79885 - 138 WP_243770648.1 hypothetical protein -
J3L21_RS33645 79955..80002 - 48 Protein_87 hypothetical protein -
J3L21_RS33650 80062..80517 - 456 WP_243770649.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10205.76 Da        Isoelectric Point: 9.3469

>T197114 WP_090532546.1 NZ_CP071880:c76326-76072 [Mucilaginibacter rubeus]
VKIIFQNPAWEDYLYWQTTDKSILKKINSLIKEIERTPYEGSGKPEPLKHNLAGWWSRRINLEHRLIYRVEADAIFILQC
RYHY

Download         Length: 255 bp

>T197114 NZ_CP095724:2535783-2536130 [Listeria innocua]
CTGATGGTGAAGCGTGGTGACGTTTACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATAAGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATTGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CGAAGTTGCCAACACATGTGGAAGCTACTCGTAAAGACGGCTTTGAAAGAGATTCTGTCATTCTATTAGAACAAATTAGA
ACGATAGATAAACAACGCCTGACAGATAAGATTACACATTTGGACGAGGAACTAATGGCCAAGGTAAATCAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9776.16 Da        Isoelectric Point: 5.7377

>AT197114 WP_090532548.1 NZ_CP071880:c76577-76323 [Mucilaginibacter rubeus]
MEITTYTAFRQQLKSFLDKVRNDHKPLVVTSANAEDIVVISKADYESMEETFYLLKSPKNAERLLHGIQEYEKGLGKERK
LLEE

Download         Length: 255 bp

>AT197114 NZ_CP095724:2535501-2535779 [Listeria innocua]
GTGTTAGAGAAAGAAAAACGGACGATAATATCCGTAGAACTGACACAGGAAATGGTACAAGAACTCGACGTAGTTGTAGA
AAAAGAAAAAATGGGGCGGAGTGAAGTTATAATGGAAGCAACGCAACAATTTTTACAGGAGAAAAGAGCTCGTGAATTAA
GAGACGAGATGGAACGCGGCTATGCAGAAATGGCGACGATTAATTTCGCCATTGCGTGCGAGTGTACTCATGTCGAAGCA
GAGGCAGAAGACAGGAATATTAGTATTTTAGGAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References