Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 79497..80002 Replicon chromosome
Accession NZ_CP071879
Organism Mucilaginibacter rubeus strain P2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3L19_RS00435 Protein ID WP_090532546.1
Coordinates 79497..79751 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3L19_RS00440 Protein ID WP_090532548.1
Coordinates 79748..80002 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3L19_RS00415 (J3L19_00415) 74858..75967 - 1110 WP_112655604.1 type III polyketide synthase -
J3L19_RS00420 (J3L19_00420) 75986..76513 - 528 WP_112655606.1 YceI family protein -
J3L19_RS00425 (J3L19_00425) 76644..77528 + 885 WP_112655608.1 UbiA family prenyltransferase -
J3L19_RS00430 (J3L19_00430) 77664..79451 - 1788 WP_112655609.1 DUF885 domain-containing protein -
J3L19_RS00435 (J3L19_00435) 79497..79751 - 255 WP_090532546.1 Txe/YoeB family addiction module toxin Toxin
J3L19_RS00440 (J3L19_00440) 79748..80002 - 255 WP_090532548.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J3L19_RS00445 (J3L19_00445) 80111..82957 - 2847 WP_112655611.1 excinuclease ABC subunit UvrA -
J3L19_RS33665 83173..83310 - 138 WP_243770648.1 hypothetical protein -
J3L19_RS33670 83380..83427 - 48 Protein_90 hypothetical protein -
J3L19_RS33675 83487..83942 - 456 WP_243770649.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10205.76 Da        Isoelectric Point: 9.3469

>T197113 WP_090532546.1 NZ_CP071879:c79751-79497 [Mucilaginibacter rubeus]
VKIIFQNPAWEDYLYWQTTDKSILKKINSLIKEIERTPYEGSGKPEPLKHNLAGWWSRRINLEHRLIYRVEADAIFILQC
RYHY

Download         Length: 255 bp

>T197113 NZ_CP095723:484566-484913 [Listeria innocua]
CTGATGGTGAAGCGTGGTGACGTTTACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATAAGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATCGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CGAAGTTGCCAACACATGTGGAAGCTACTCGTAAAGACGGCTTTGAAAGAGATTCTGTCATTCTATTAGAACAAATTAGA
ACGATAGATAAACAACGCCTGACAGATAAGATTACGCATTTGGACGAGGAACTAATGGCCAAGGTAAATCAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9776.16 Da        Isoelectric Point: 5.7377

>AT197113 WP_090532548.1 NZ_CP071879:c80002-79748 [Mucilaginibacter rubeus]
MEITTYTAFRQQLKSFLDKVRNDHKPLVVTSANAEDIVVISKADYESMEETFYLLKSPKNAERLLHGIQEYEKGLGKERK
LLEE

Download         Length: 255 bp

>AT197113 NZ_CP095723:484284-484562 [Listeria innocua]
GTGTTAGAGAAAGAAAAACGGATGATAATTTCCGTAGAACTGACACAGGAAATGGTACAAGAACTCGACGTAGTTGTAGA
AAAAGAAAAAATGGGGCGGAGTGAAGTTATAATGGAAGCAACGCAACAATTTTTACAGGAGAAAAGAGCTCGTGAATTAA
GAGACGAGATGGAACGCGGCTATGCAGAAATGGCGACGATTAATTTCGCTATCGCGTGCGAGTGTACTCATGTCGAAGCA
GAGGCAGAAGACAGGAATATTAGTATTTTAGGAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References