Detailed information of TA system TA197112

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-RelB
• Location: 4747572..4748077
• Replicon: chromosome
• Accession: NZ_CP071878
• Organism: Mucilaginibacter gossypii strain P3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J3L18_RS20505
• Protein ID: WP_090532546.1
• Coordinates: 4747572..4747826 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J3L18_RS20510
• Protein ID: WP_090532548.1
• Coordinates: 4747823..4748077 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J3L18_RS20485 (J3L18_20485)	4742939..4744048	-	1110	WP_129568195.1	type III polyketide synthase	-
J3L18_RS20490 (J3L18_20490)	4744067..4744594	-	528	WP_129568194.1	YceI family protein	-
J3L18_RS20495 (J3L18_20495)	4744725..4745609	+	885	WP_129568193.1	UbiA family prenyltransferase	-
J3L18_RS20500 (J3L18_20500)	4745739..4747526	-	1788	WP_129568192.1	DUF885 domain-containing protein	-
J3L18_RS20505 (J3L18_20505)	4747572..4747826	-	255	WP_090532546.1	Txe/YoeB family addiction module toxin	Toxin
J3L18_RS20510 (J3L18_20510)	4747823..4748077	-	255	WP_090532548.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
J3L18_RS20515 (J3L18_20515)	4748186..4751032	-	2847	WP_129568191.1	excinuclease ABC subunit UvrA	-
J3L18_RS20520 (J3L18_20520)	4751248..4752033	-	786	WP_243771435.1	lytic transglycosylase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10205.76 Da
• Isoelectric Point: 9.3469

>T197112 WP_090532546.1 NZ_CP071878:c4747826-4747572 [Mucilaginibacter gossypii]
VKIIFQNPAWEDYLYWQTTDKSILKKINSLIKEIERTPYEGSGKPEPLKHNLAGWWSRRINLEHRLIYRVEADAIFILQC
RYHY

Nucleotide

• Length: 255 bp

>T197112 NZ_CP095722:c26066-25791 [Listeria innocua]
ATGAGTAAACATTTTCATGTGAGATTTGAAAAAGAAGCTCAAAAAGTATTAAAAAAGATGGATAGATTTCAAGCAAAATT
GATATTATCCTGGATTGAAAAACATATTGAAGGTACTGATGATCCAAGACAACATGGTAAAAGTCTTGTTGGTAACCGGA
GTGGACAATGGCGATATAGGGTTGGAGATTATCGCTTAATTGCAGAGATTCAAGATAATGAAGTGATAGTGTTAATTTTA
AACATCGGACACAGGAGAGATATTTACGATAAATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9776.16 Da
• Isoelectric Point: 5.7377

>AT197112 WP_090532548.1 NZ_CP071878:c4748077-4747823 [Mucilaginibacter gossypii]
MEITTYTAFRQQLKSFLDKVRNDHKPLVVTSANAEDIVVISKADYESMEETFYLLKSPKNAERLLHGIQEYEKGLGKERK
LLEE

Nucleotide

• Length: 255 bp

>AT197112 NZ_CP095722:c26284-26063 [Listeria innocua]
ATGACTACCATTACATTTCGAGTATCTGATAAAGAAAAAGCGTTTATTCAAGAAATGGCTAAGCTTAACGGTATCTCTAT
TTCAGAACTTAGTCGTAAAAAGATTATAGAAGGTTTAGAAGATCAAATTGATTTACAATCGTATGAGCGTGCTATAAAGG
CGCATCAAGTGAAAGATGAAAGTATTTCTTTTGATGAAATGAAAAAGGAACTTGAATTATGA