Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1462734..1463416 Replicon chromosome
Accession NZ_CP071876
Organism Enterobacter hormaechei strain GX4-8L

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag J4O68_RS07135 Protein ID WP_235155439.1
Coordinates 1462734..1463075 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag J4O68_RS07140 Protein ID WP_235155440.1
Coordinates 1463096..1463416 (-) Length 107 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4O68_RS07100 (J4O68_07085) 1458823..1459014 + 192 WP_071785715.1 YecR family lipoprotein -
J4O68_RS07105 (J4O68_07090) 1459037..1459393 - 357 WP_032608610.1 hypothetical protein -
J4O68_RS07110 (J4O68_07095) 1459396..1459938 - 543 WP_032608608.1 type IV secretion protein Rhs -
J4O68_RS07115 (J4O68_07100) 1460044..1460202 - 159 WP_023315491.1 hypothetical protein -
J4O68_RS07120 (J4O68_07105) 1460554..1460820 - 267 WP_235155437.1 hypothetical protein -
J4O68_RS07125 (J4O68_07110) 1461085..1461699 - 615 WP_220721905.1 hypothetical protein -
J4O68_RS07130 (J4O68_07115) 1461731..1462501 - 771 WP_235155438.1 hypothetical protein -
J4O68_RS07135 (J4O68_07120) 1462734..1463075 - 342 WP_235155439.1 TA system toxin CbtA family protein Toxin
J4O68_RS07140 (J4O68_07125) 1463096..1463416 - 321 WP_235155440.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
J4O68_RS07145 (J4O68_07130) 1463435..1463656 - 222 WP_235155441.1 DUF987 domain-containing protein -
J4O68_RS07150 (J4O68_07135) 1463665..1464147 - 483 WP_235155442.1 DNA repair protein RadC -
J4O68_RS07155 (J4O68_07140) 1464156..1464620 - 465 WP_235155443.1 antirestriction protein -
J4O68_RS07160 (J4O68_07145) 1464762..1467605 - 2844 WP_235155444.1 Ag43/Cah family autotransporter adhesin -
J4O68_RS07165 (J4O68_07150) 1467678..1468364 - 687 WP_235155445.1 WYL domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1458498..1490467 31969


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-108)

Antitoxin

(6-105)


Sequences


Toxin        


Download         Length: 114 a.a.        Molecular weight: 12758.84 Da        Isoelectric Point: 8.0566

>T197101 WP_235155439.1 NZ_CP071876:c1463075-1462734 [Enterobacter hormaechei]
MKTLPATISQAAKPCLSPVAVWQMLLIRLLEQHYGLTLNDTPFSDETVIKEHIDAGISLANAVNFLVEKYELVRIDRRGF
NRQEQSPYLLAVDILRARQAIGLLRQNHPPSIP

Download         Length: 342 bp

>T197101 NZ_CP095557:791959-792369 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATAGCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11850.42 Da        Isoelectric Point: 6.4742

>AT197101 WP_235155440.1 NZ_CP071876:c1463416-1463096 [Enterobacter hormaechei]
MSSNVTWGLQRNISPLLEAHLVQGGNRLHYLADRASITGKFSDDECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTIY
HNGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 321 bp

>AT197101 NZ_CP095557:791712-791978 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References