Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yfjZ-ypjF/CbtA-CbeA |
Location | 1462734..1463416 | Replicon | chromosome |
Accession | NZ_CP071876 | ||
Organism | Enterobacter hormaechei strain GX4-8L |
Toxin (Protein)
Gene name | ypjF | Uniprot ID | - |
Locus tag | J4O68_RS07135 | Protein ID | WP_235155439.1 |
Coordinates | 1462734..1463075 (-) | Length | 114 a.a. |
Antitoxin (Protein)
Gene name | yfjZ | Uniprot ID | - |
Locus tag | J4O68_RS07140 | Protein ID | WP_235155440.1 |
Coordinates | 1463096..1463416 (-) | Length | 107 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
J4O68_RS07100 (J4O68_07085) | 1458823..1459014 | + | 192 | WP_071785715.1 | YecR family lipoprotein | - |
J4O68_RS07105 (J4O68_07090) | 1459037..1459393 | - | 357 | WP_032608610.1 | hypothetical protein | - |
J4O68_RS07110 (J4O68_07095) | 1459396..1459938 | - | 543 | WP_032608608.1 | type IV secretion protein Rhs | - |
J4O68_RS07115 (J4O68_07100) | 1460044..1460202 | - | 159 | WP_023315491.1 | hypothetical protein | - |
J4O68_RS07120 (J4O68_07105) | 1460554..1460820 | - | 267 | WP_235155437.1 | hypothetical protein | - |
J4O68_RS07125 (J4O68_07110) | 1461085..1461699 | - | 615 | WP_220721905.1 | hypothetical protein | - |
J4O68_RS07130 (J4O68_07115) | 1461731..1462501 | - | 771 | WP_235155438.1 | hypothetical protein | - |
J4O68_RS07135 (J4O68_07120) | 1462734..1463075 | - | 342 | WP_235155439.1 | TA system toxin CbtA family protein | Toxin |
J4O68_RS07140 (J4O68_07125) | 1463096..1463416 | - | 321 | WP_235155440.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
J4O68_RS07145 (J4O68_07130) | 1463435..1463656 | - | 222 | WP_235155441.1 | DUF987 domain-containing protein | - |
J4O68_RS07150 (J4O68_07135) | 1463665..1464147 | - | 483 | WP_235155442.1 | DNA repair protein RadC | - |
J4O68_RS07155 (J4O68_07140) | 1464156..1464620 | - | 465 | WP_235155443.1 | antirestriction protein | - |
J4O68_RS07160 (J4O68_07145) | 1464762..1467605 | - | 2844 | WP_235155444.1 | Ag43/Cah family autotransporter adhesin | - |
J4O68_RS07165 (J4O68_07150) | 1467678..1468364 | - | 687 | WP_235155445.1 | WYL domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1458498..1490467 | 31969 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12758.84 Da Isoelectric Point: 8.0566
>T197101 WP_235155439.1 NZ_CP071876:c1463075-1462734 [Enterobacter hormaechei]
MKTLPATISQAAKPCLSPVAVWQMLLIRLLEQHYGLTLNDTPFSDETVIKEHIDAGISLANAVNFLVEKYELVRIDRRGF
NRQEQSPYLLAVDILRARQAIGLLRQNHPPSIP
MKTLPATISQAAKPCLSPVAVWQMLLIRLLEQHYGLTLNDTPFSDETVIKEHIDAGISLANAVNFLVEKYELVRIDRRGF
NRQEQSPYLLAVDILRARQAIGLLRQNHPPSIP
Download Length: 342 bp
>T197101 NZ_CP095557:791959-792369 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATAGCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATAGCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA
Antitoxin
Download Length: 107 a.a. Molecular weight: 11850.42 Da Isoelectric Point: 6.4742
>AT197101 WP_235155440.1 NZ_CP071876:c1463416-1463096 [Enterobacter hormaechei]
MSSNVTWGLQRNISPLLEAHLVQGGNRLHYLADRASITGKFSDDECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTIY
HNGFTCEADTLGSCGYVYIAVYPTQR
MSSNVTWGLQRNISPLLEAHLVQGGNRLHYLADRASITGKFSDDECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTIY
HNGFTCEADTLGSCGYVYIAVYPTQR
Download Length: 321 bp
>AT197101 NZ_CP095557:791712-791978 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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