Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/ParE-YefM |
| Location | 1494487..1495032 | Replicon | chromosome |
| Accession | NZ_CP071857 | ||
| Organism | Vibrio sp. SCSIO 43145 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | J4N38_RS07265 | Protein ID | WP_252036463.1 |
| Coordinates | 1494487..1494783 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | A0A7X8YLC8 |
| Locus tag | J4N38_RS07270 | Protein ID | WP_005526987.1 |
| Coordinates | 1494790..1495032 (-) | Length | 81 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J4N38_RS07220 (J4N38_07160) | 1490255..1490509 | + | 255 | WP_252036457.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | - |
| J4N38_RS07225 (J4N38_07165) | 1490502..1490771 | + | 270 | WP_252036458.1 | Txe/YoeB family addiction module toxin | - |
| J4N38_RS07230 (J4N38_07170) | 1490950..1491264 | + | 315 | WP_252036459.1 | hypothetical protein | - |
| J4N38_RS07235 (J4N38_07180) | 1491821..1491973 | + | 153 | WP_252036460.1 | hypothetical protein | - |
| J4N38_RS07240 (J4N38_07185) | 1491974..1492738 | + | 765 | WP_252036619.1 | PhzF family phenazine biosynthesis protein | - |
| J4N38_RS07245 (J4N38_07190) | 1492756..1492845 | + | 90 | WP_239871702.1 | DUF3265 domain-containing protein | - |
| J4N38_RS07250 (J4N38_07195) | 1492873..1493142 | + | 270 | WP_252036461.1 | hypothetical protein | - |
| J4N38_RS07255 (J4N38_07200) | 1493287..1493706 | + | 420 | WP_252036358.1 | hypothetical protein | - |
| J4N38_RS07260 (J4N38_07205) | 1493830..1494315 | + | 486 | WP_252036462.1 | GNAT family N-acetyltransferase | - |
| J4N38_RS07265 (J4N38_07210) | 1494487..1494783 | - | 297 | WP_252036463.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| J4N38_RS07270 (J4N38_07215) | 1494790..1495032 | - | 243 | WP_005526987.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| J4N38_RS07280 | 1496851..1496994 | + | 144 | WP_252036465.1 | hypothetical protein | - |
| J4N38_RS07285 | 1497013..1497243 | + | 231 | WP_252036466.1 | hypothetical protein | - |
| J4N38_RS07290 (J4N38_07230) | 1497465..1498805 | - | 1341 | WP_252036467.1 | BspA family leucine-rich repeat surface protein | - |
| J4N38_RS07295 (J4N38_07235) | 1498844..1499281 | - | 438 | WP_252036468.1 | BspA family leucine-rich repeat surface protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1344026..1496374 | 152348 | |
| - | inside | Integron | - | - | 1343019..1495238 | 152219 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11249.88 Da Isoelectric Point: 9.8450
>T197062 WP_252036463.1 NZ_CP071857:c1494783-1494487 [Vibrio sp. SCSIO 43145]
MQKNKYKLSKLAQTHLRKIKSYTVNNFSETQWRSYKDTLLTGFQMLADNPAVGRSCDDIYPSGFYFPVGKHTAYFTKEDG
FILVVAILGQSQLPQNHL
MQKNKYKLSKLAQTHLRKIKSYTVNNFSETQWRSYKDTLLTGFQMLADNPAVGRSCDDIYPSGFYFPVGKHTAYFTKEDG
FILVVAILGQSQLPQNHL
Download Length: 297 bp
>T197062 NZ_CP095538:c2282936-2282760 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTGGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCAAGGGCGACGCAGTGTCATGCCGCGTCACCCCAGTGATGAGATAAAAGAACCATTGCGTAAAGCAATCCTGAAGC
AACTCGGTTTGAGTTAA
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTGGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCAAGGGCGACGCAGTGTCATGCCGCGTCACCCCAGTGATGAGATAAAAGAACCATTGCGTAAAGCAATCCTGAAGC
AACTCGGTTTGAGTTAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8974.16 Da Isoelectric Point: 4.7914
>AT197062 WP_005526987.1 NZ_CP071857:c1495032-1494790 [Vibrio sp. SCSIO 43145]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKTDYLKHCFESAKQDLAQGNVVDGEDFLNAL
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKTDYLKHCFESAKQDLAQGNVVDGEDFLNAL
Download Length: 243 bp
>AT197062 NZ_CP095538:c2282714-2282298 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACAGTTGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ATGAGCTAATCCCGTTGCCTTCGCCATTAACTAACAACGATCACTTTATTGAAGTGCCTTTAAGTATCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGACGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAATTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACAGTTGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ATGAGCTAATCCCGTTGCCTTCGCCATTAACTAACAACGATCACTTTATTGAAGTGCCTTTAAGTATCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGACGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAATTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|