Detailed information of TA system TA197059

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1470980..1471539
• Replicon: chromosome
• Accession: NZ_CP071857
• Organism: Vibrio sp. SCSIO 43145

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J4N38_RS07070
• Protein ID: WP_252036435.1
• Coordinates: 1470980..1471258 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: J4N38_RS07075
• Protein ID: WP_252036436.1
• Coordinates: 1471255..1471539 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J4N38_RS07030 (J4N38_06975)	1466284..1466679	+	396	WP_252036428.1	cupin domain-containing protein	-
J4N38_RS07035 (J4N38_06980)	1466820..1467230	+	411	WP_252036429.1	hypothetical protein	-
J4N38_RS07040 (J4N38_06985)	1467369..1467746	+	378	WP_252040102.1	DUF1851 domain-containing protein	-
J4N38_RS07045 (J4N38_06990)	1468118..1468435	+	318	WP_252036431.1	GNAT family N-acetyltransferase	-
J4N38_RS07050 (J4N38_06995)	1468582..1469013	+	432	WP_252036432.1	hypothetical protein	-
J4N38_RS22755	1469051..1469182	+	132	WP_255906341.1	hypothetical protein	-
J4N38_RS07055 (J4N38_07000)	1469321..1469794	+	474	WP_252036433.1	GrpB family protein	-
J4N38_RS07060 (J4N38_07005)	1469941..1470357	+	417	WP_252036434.1	GFA family protein	-
J4N38_RS07065 (J4N38_07010)	1470846..1470950	+	105	WP_252036618.1	DUF3265 domain-containing protein	-
J4N38_RS07070 (J4N38_07015)	1470980..1471258	-	279	WP_252036435.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J4N38_RS07075 (J4N38_07020)	1471255..1471539	-	285	WP_252036436.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
J4N38_RS07080 (J4N38_07025)	1472211..1472696	-	486	WP_252036437.1	hypothetical protein	-
J4N38_RS07085 (J4N38_07030)	1472847..1472939	+	93	WP_193837464.1	DUF3265 domain-containing protein	-
J4N38_RS07090 (J4N38_07035)	1473821..1473970	+	150	WP_252036438.1	hypothetical protein	-
J4N38_RS07095 (J4N38_07040)	1474479..1474919	+	441	WP_252036439.1	hypothetical protein	-
J4N38_RS07100 (J4N38_07045)	1475821..1476209	+	389	Protein_1372	lysozyme inhibitor LprI family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1344026..1496374	152348
	-	inside	Integron	-	-	1343019..1495238	152219

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-44)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10934.60 Da
• Isoelectric Point: 4.4755

>T197059 WP_252036435.1 NZ_CP071857:c1471258-1470980 [Vibrio sp. SCSIO 43145]
MIFWEEESLNDREKIFEFLYDFNPEAAEKTDEVIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPAS

Nucleotide

• Length: 279 bp

>T197059 NZ_CP095538:1828493-1828596 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10938.31 Da
• Isoelectric Point: 9.1865

>AT197059 WP_252036436.1 NZ_CP071857:c1471539-1471255 [Vibrio sp. SCSIO 43145]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQVNLAFEKFDLGKANFVDHESAKSR
MAERKAKIRNRGKV

Nucleotide

• Length: 285 bp

>AT197059 NZ_CP095538:c1828634-1828363 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT