Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE(toxin) |
| Location | 1445463..1446022 | Replicon | chromosome |
| Accession | NZ_CP071857 | ||
| Organism | Vibrio sp. SCSIO 43145 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | J4N38_RS06880 | Protein ID | WP_252036435.1 |
| Coordinates | 1445463..1445741 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | J4N38_RS06885 | Protein ID | WP_252036436.1 |
| Coordinates | 1445738..1446022 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J4N38_RS06840 | 1440769..1440960 | + | 192 | WP_252040096.1 | hypothetical protein | - |
| J4N38_RS06845 | 1440923..1441162 | + | 240 | WP_252040097.1 | cupin domain-containing protein | - |
| J4N38_RS06850 (J4N38_06795) | 1441303..1441713 | + | 411 | WP_252036429.1 | hypothetical protein | - |
| J4N38_RS06855 (J4N38_06800) | 1441852..1442313 | + | 462 | WP_252036430.1 | DUF1851 domain-containing protein | - |
| J4N38_RS06860 (J4N38_06805) | 1442602..1442919 | + | 318 | WP_252036431.1 | GNAT family N-acetyltransferase | - |
| J4N38_RS06865 (J4N38_06810) | 1443066..1443497 | + | 432 | WP_252036432.1 | hypothetical protein | - |
| J4N38_RS22750 | 1443535..1443666 | + | 132 | WP_255906341.1 | hypothetical protein | - |
| J4N38_RS06870 (J4N38_06815) | 1443805..1444278 | + | 474 | WP_252036433.1 | GrpB family protein | - |
| J4N38_RS06875 (J4N38_06820) | 1444426..1444842 | + | 417 | WP_252036434.1 | GFA family protein | - |
| J4N38_RS06880 (J4N38_06825) | 1445463..1445741 | - | 279 | WP_252036435.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| J4N38_RS06885 (J4N38_06830) | 1445738..1446022 | - | 285 | WP_252036436.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| J4N38_RS06890 (J4N38_06835) | 1446701..1447186 | - | 486 | WP_252036437.1 | hypothetical protein | - |
| J4N38_RS06895 (J4N38_06840) | 1447337..1447429 | + | 93 | WP_193837464.1 | DUF3265 domain-containing protein | - |
| J4N38_RS06900 (J4N38_06845) | 1448312..1448461 | + | 150 | WP_252036438.1 | hypothetical protein | - |
| J4N38_RS06905 (J4N38_06850) | 1448969..1449409 | + | 441 | WP_252036439.1 | hypothetical protein | - |
| J4N38_RS06910 (J4N38_06855) | 1450281..1450700 | + | 420 | WP_252036440.1 | lysozyme inhibitor LprI family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1344026..1496374 | 152348 | |
| - | inside | Integron | - | - | 1343019..1495238 | 152219 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10934.60 Da Isoelectric Point: 4.4755
>T197058 WP_252036435.1 NZ_CP071857:c1445741-1445463 [Vibrio sp. SCSIO 43145]
MIFWEEESLNDREKIFEFLYDFNPEAAEKTDEVIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPAS
MIFWEEESLNDREKIFEFLYDFNPEAAEKTDEVIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPAS
Download Length: 279 bp
>T197058 NZ_CP095538:c1630562-1630188 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCTTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCACGCCGGGCAACCGGCCTGATGCCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCTTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCACGCCGGGCAACCGGCCTGATGCCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10938.31 Da Isoelectric Point: 9.1865
>AT197058 WP_252036436.1 NZ_CP071857:c1446022-1445738 [Vibrio sp. SCSIO 43145]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQVNLAFEKFDLGKANFVDHESAKSR
MAERKAKIRNRGKV
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQVNLAFEKFDLGKANFVDHESAKSR
MAERKAKIRNRGKV
Download Length: 285 bp
>AT197058 NZ_CP095538:c1631019-1630651 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|