Detailed information of TA system TA197048

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1662701..1663614
• Replicon: chromosome
• Accession: NZ_CP071850
• Organism: Vibrio sp. SCSIO 43140

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: J4N45_RS07855
• Protein ID: WP_252014416.1
• Coordinates: 1663144..1663614 (+)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: J4N45_RS07850
• Protein ID: WP_252014414.1
• Coordinates: 1662701..1663144 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J4N45_RS07830 (J4N45_07840)	1657866..1659905	+	2040	WP_252014409.1	methyl-accepting chemotaxis protein	-
J4N45_RS07835 (J4N45_07845)	1659902..1660702	-	801	WP_252014411.1	sterol desaturase family protein	-
J4N45_RS07840 (J4N45_07850)	1660778..1661512	+	735	WP_252014412.1	tRNA-uridine aminocarboxypropyltransferase	-
J4N45_RS07845 (J4N45_07855)	1661669..1662577	+	909	WP_128648638.1	N-acetylglucosamine kinase	-
J4N45_RS07850 (J4N45_07860)	1662701..1663144	+	444	WP_252014414.1	DUF2384 domain-containing protein	Antitoxin
J4N45_RS07855 (J4N45_07865)	1663144..1663614	+	471	WP_252014416.1	RES domain-containing protein	Toxin
J4N45_RS07860 (J4N45_07870)	1663586..1664506	-	921	WP_252014417.1	lipid kinase YegS	-
J4N45_RS07865 (J4N45_07875)	1664539..1665342	-	804	WP_252014418.1	Cof-type HAD-IIB family hydrolase	-
J4N45_RS07870 (J4N45_07880)	1665493..1666173	+	681	WP_252014419.1	7-carboxy-7-deazaguanine synthase QueE	-
J4N45_RS07875 (J4N45_07885)	1666209..1666895	+	687	WP_252014420.1	7-cyano-7-deazaguanine synthase QueC	-
J4N45_RS07880 (J4N45_07890)	1666926..1667285	-	360	WP_042475668.1	DUF2750 domain-containing protein	-
J4N45_RS07885 (J4N45_07895)	1667408..1668031	-	624	WP_252014422.1	OmpA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-136)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (29-88)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 17964.33 Da
• Isoelectric Point: 4.3059

>T197048 WP_252014416.1 NZ_CP071850:1663144-1663614 [Vibrio sp. SCSIO 43140]
MFLYRIVKKKFATNIEQVFDGEGARRYGGRWNSAGNRCVYLATSESLAILEVLVHLNDTELLNDYDLYRIDIEEALIIEL
DQSYLPDDWQEDPAPSSTAQIGDEWLESEMSLCLKIPSTIVPREFNCLLNIQHAAFNLEQLEVVKLAFNPDHRLSR

Nucleotide

• Length: 471 bp

>T197048 NZ_CP095533:4688879-4689343 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCCATTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16534.80 Da
• Isoelectric Point: 9.9506

>AT197048 WP_252014414.1 NZ_CP071850:1662701-1663144 [Vibrio sp. SCSIO 43140]
MTASTKFVPSRSTAGFWSQIGVPPRGRKLHEAIEAGFDYATYQKLANVTGIEKKELARITNIKSATLSRRAKDGKFSSEE
SDRLYRYAEVYNASLRLFEDNKLKAFQWMHNPVKALGYVAPSDMLKTSAETEEVLSVIGRLEHGVFN

Nucleotide

• Length: 444 bp

>AT197048 NZ_CP095533:4688544-4688879 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACACC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA