Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 1005831..1006371 | Replicon | chromosome |
| Accession | NZ_CP071849 | ||
| Organism | Vibrio sp. SCSIO 43136 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | J4N39_RS19430 | Protein ID | WP_252023999.1 |
| Coordinates | 1006102..1006371 (+) | Length | 90 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | J4N39_RS19425 | Protein ID | WP_252023997.1 |
| Coordinates | 1005831..1006115 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J4N39_RS19380 (J4N39_19390) | 1001352..1001978 | - | 627 | WP_252023984.1 | LysE family translocator | - |
| J4N39_RS19385 (J4N39_19395) | 1002075..1002536 | - | 462 | WP_252023985.1 | RidA family protein | - |
| J4N39_RS19390 (J4N39_19400) | 1002593..1002970 | - | 378 | WP_252023986.1 | hypothetical protein | - |
| J4N39_RS19395 (J4N39_19405) | 1002967..1003308 | - | 342 | WP_252023987.1 | DUF4144 domain-containing protein | - |
| J4N39_RS19400 (J4N39_19410) | 1003482..1003703 | + | 222 | WP_252023988.1 | ParD-like family protein | - |
| J4N39_RS19405 (J4N39_19415) | 1003696..1003986 | + | 291 | WP_252023990.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| J4N39_RS19410 (J4N39_19420) | 1004120..1004653 | - | 534 | WP_252023992.1 | GNAT family N-acetyltransferase | - |
| J4N39_RS19415 (J4N39_19425) | 1004650..1004919 | - | 270 | WP_252023994.1 | DUF1778 domain-containing protein | - |
| J4N39_RS19420 (J4N39_19430) | 1005153..1005635 | - | 483 | WP_252023995.1 | tetratricopeptide repeat protein | - |
| J4N39_RS19425 (J4N39_19435) | 1005831..1006115 | + | 285 | WP_252023997.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| J4N39_RS19430 (J4N39_19440) | 1006102..1006371 | + | 270 | WP_252023999.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| J4N39_RS19435 (J4N39_19445) | 1006457..1007405 | + | 949 | Protein_903 | IS110 family transposase | - |
| J4N39_RS19440 (J4N39_19450) | 1007784..1008098 | - | 315 | WP_252024001.1 | DNA-binding transcriptional regulator | - |
| J4N39_RS19445 (J4N39_19455) | 1008085..1008417 | - | 333 | WP_252024003.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| J4N39_RS19450 (J4N39_19460) | 1008612..1009229 | - | 618 | WP_252024005.1 | LysE family translocator | - |
| J4N39_RS19455 (J4N39_19465) | 1009389..1010588 | + | 1200 | WP_252026849.1 | IS4 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 1007028..1007405 | 377 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10267.00 Da Isoelectric Point: 9.0920
>T197046 WP_252023999.1 NZ_CP071849:1006102-1006371 [Vibrio sp. SCSIO 43136]
MYLLEYSTQFKKDFKKVTKLPIPDVIEVGNIISKLQRGETLCAKNVDHPLSGNWAGFRDCHIKPDLLLIYRVHEKTLQLA
RIGSHSELF
MYLLEYSTQFKKDFKKVTKLPIPDVIEVGNIISKLQRGETLCAKNVDHPLSGNWAGFRDCHIKPDLLLIYRVHEKTLQLA
RIGSHSELF
Download Length: 270 bp
>T197046 NZ_CP095533:c4356231-4355824 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGACGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGACGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10251.61 Da Isoelectric Point: 5.5305
>AT197046 WP_252023997.1 NZ_CP071849:1005831-1006115 [Vibrio sp. SCSIO 43136]
MKNEMLSTRIDHDTKVAFTNICDEVGLSPSQAIKLFARAVINHGGIPFELKVKQPNQESIEAMHELVAGQGHKAESIDSL
FDTLTDGKVTNVSS
MKNEMLSTRIDHDTKVAFTNICDEVGLSPSQAIKLFARAVINHGGIPFELKVKQPNQESIEAMHELVAGQGHKAESIDSL
FDTLTDGKVTNVSS
Download Length: 285 bp
>AT197046 NZ_CP095533:c4356478-4356212 [Escherichia coli]
ATGGATATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGATATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|