197044

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 132427..133193 Replicon chromosome
Accession NZ_CP071849
Organism Vibrio sp. SCSIO 43136

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag J4N39_RS15485 Protein ID WP_252025550.1
Coordinates 132699..133193 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag J4N39_RS15480 Protein ID WP_252025548.1
Coordinates 132427..132702 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4N39_RS15455 (J4N39_15465) 127750..128496 - 747 WP_252025537.1 hypothetical protein -
J4N39_RS15460 (J4N39_15470) 128610..128993 - 384 WP_252025539.1 hypothetical protein -
J4N39_RS15465 (J4N39_15475) 129608..130768 + 1161 WP_252025541.1 MFS transporter -
J4N39_RS15470 (J4N39_15480) 130902..131273 - 372 WP_252025544.1 DUF413 domain-containing protein -
J4N39_RS15475 (J4N39_15485) 131412..132299 + 888 WP_252025546.1 LysR family transcriptional regulator -
J4N39_RS15480 (J4N39_15490) 132427..132702 + 276 WP_252025548.1 DUF1778 domain-containing protein Antitoxin
J4N39_RS15485 (J4N39_15495) 132699..133193 + 495 WP_252025550.1 GNAT family N-acetyltransferase Toxin
J4N39_RS15490 (J4N39_15500) 133185..134063 - 879 WP_252026914.1 LysR family transcriptional regulator -
J4N39_RS15495 (J4N39_15505) 134200..135165 + 966 WP_252025552.1 aldo/keto reductase -
J4N39_RS15500 (J4N39_15510) 135179..135568 + 390 WP_252025554.1 heme-binding protein -
J4N39_RS15505 (J4N39_15515) 135719..137236 + 1518 WP_252026916.1 nitric oxide reductase transcriptional regulator NorR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(85-150)

Antitoxin

Vibrio phage ICP1, Orf50

(7-86)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18385.99 Da        Isoelectric Point: 7.3555

>T197044 WP_252025550.1 NZ_CP071849:132699-133193 [Vibrio sp. SCSIO 43136]
MNTVLLDKAKHDRNRFNCGIEALNNYLKVMASQQAKKDNTRTFVLEDDNESSHIIGFYTLTMAPIDLKALPDQLQKKHQS
STSGGLIARLAIDERYKGKGFGEWLLIDALKKLLAASDSVAFPLVIVDAKDGAKHFYERYGFTAFQDAENKLFITISDVR
ASLD

Download         Length: 495 bp

>T197044 NZ_CP095533:c4132935-4132624 [Escherichia coli]
ATGCACATCATTTCGAAAGCGCCATTTGAAGAGTGTGCGCGCAAATATCCTAACGACGCTCTGGCTCTACACTCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCTAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9813.32 Da        Isoelectric Point: 10.0970

>AT197044 WP_252025548.1 NZ_CP071849:132427-132702 [Vibrio sp. SCSIO 43136]
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQALKLSQADAKLLMEALDQPAKPNAKLSA
ASERYKSKNQQ

Download         Length: 276 bp

>AT197044 NZ_CP095533:c4132627-4132208 [Escherichia coli]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCAGCAATGCCGGTT
GGCGTGGCGTTACTTCGTACGCTGATTGATCAACATAATTTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
TCTGGTCAGTCAGATTTTGTCTGGGCAACGATCCCTGACGATATCCCATATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References