197042

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2154298..2154836 Replicon chromosome
Accession NZ_CP071848
Organism Vibrio sp. SCSIO 43136

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J4N39_RS10150 Protein ID WP_252018790.1
Coordinates 2154537..2154836 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J4N39_RS10145 Protein ID WP_252018788.1
Coordinates 2154298..2154540 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4N39_RS10125 (J4N39_10130) 2149361..2150668 - 1308 WP_252018779.1 isochorismate synthase MenF -
J4N39_RS10130 (J4N39_10135) 2150974..2152188 + 1215 WP_252018781.1 pyridoxal phosphate-dependent aminotransferase -
J4N39_RS10135 (J4N39_10140) 2152264..2152848 + 585 WP_252018783.1 5'-deoxynucleotidase -
J4N39_RS10140 (J4N39_10145) 2152893..2154221 + 1329 WP_252018785.1 anti-phage deoxyguanosine triphosphatase -
J4N39_RS10145 (J4N39_10150) 2154298..2154540 + 243 WP_252018788.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
J4N39_RS10150 (J4N39_10155) 2154537..2154836 + 300 WP_252018790.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4N39_RS10155 (J4N39_10160) 2154849..2155445 - 597 WP_286036800.1 DTW domain-containing protein -
J4N39_RS10160 (J4N39_10165) 2155451..2156002 + 552 WP_252018794.1 rhombosortase -
J4N39_RS10165 (J4N39_10170) 2156076..2156363 + 288 WP_252018796.1 hypothetical protein -
J4N39_RS10170 (J4N39_10175) 2156425..2156682 - 258 WP_252018799.1 CcdB family protein -
J4N39_RS10175 (J4N39_10180) 2156718..2156957 - 240 WP_252018801.1 type II toxin-antitoxin system CcdA family antitoxin -
J4N39_RS10180 (J4N39_10185) 2157028..2157321 - 294 WP_252018803.1 ComEA family DNA-binding protein -
J4N39_RS10185 (J4N39_10190) 2157476..2159335 - 1860 WP_252018805.1 peptidylprolyl isomerase -
J4N39_RS10190 (J4N39_10195) 2159541..2159813 - 273 WP_252018807.1 HU family DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11865.84 Da        Isoelectric Point: 10.5165

>T197042 WP_252018790.1 NZ_CP071848:2154537-2154836 [Vibrio sp. SCSIO 43136]
MKPFQLTNRAKLDLKDIAIFTARRWGREQRNLYLKQFDDSFWLLAENPDIGKICDEIRQGYRKFPQGSHVIFYRLIGNQK
IEIIRILHKSMDVNPLFAR

Download         Length: 300 bp

>T197042 NZ_CP095533:c2786350-2785028 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAATGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAACCGTTATGCCAGACCGTTATCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCTGTATTTAACTTCTTCGATAACCTGCTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGATAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAACAGCTCACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTGCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTGTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTATTGGGTGGCGCAGGAATACACAT
CAGCGATCTCAAACTAGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTTCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGGCCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9046.96 Da        Isoelectric Point: 4.2690

>AT197042 WP_252018788.1 NZ_CP071848:2154298-2154540 [Vibrio sp. SCSIO 43136]
MAKNTSITLGKHFDGFIADQIQSGRYNSASEVIRSALRLLESQETKMHTLRQLLVEGEESGTADYDLDSFIEELDEEPNR

Download         Length: 243 bp

>AT197042 NZ_CP095533:c2786616-2786350 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTAGCGAATGCAATGAAACTGGTTCGTCAGCAAAATGGCTGGAC
GCAGAGCGGGCTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TGACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References