Detailed information of TA system TA197041

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafN(antitoxin)
• Location: 1719542..1720107
• Replicon: chromosome
• Accession: NZ_CP071848
• Organism: Vibrio sp. SCSIO 43136

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J4N39_RS07990
• Protein ID: WP_252017846.1
• Coordinates: 1719542..1719829 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: J4N39_RS07995
• Protein ID: WP_252017848.1
• Coordinates: 1719826..1720107 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J4N39_RS07955 (J4N39_07985)	1715601..1716263	+	663	WP_252017831.1	cupin domain-containing protein	-
J4N39_RS07960 (J4N39_07990)	1716275..1716880	-	606	WP_252017833.1	sugar O-acetyltransferase	-
J4N39_RS07965 (J4N39_07995)	1716927..1717712	-	786	WP_252017835.1	protein-tyrosine phosphatase family protein	-
J4N39_RS07970 (J4N39_08000)	1717803..1718048	-	246	WP_252017837.1	Rho-binding antiterminator	-
J4N39_RS07975 (J4N39_08005)	1718086..1718544	-	459	WP_252017840.1	GNAT family N-acetyltransferase	-
J4N39_RS07980 (J4N39_08010)	1718837..1719121	+	285	WP_252017842.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
J4N39_RS07985 (J4N39_08015)	1719118..1719396	+	279	WP_252017844.1	type II toxin-antitoxin system RelE/ParE family toxin	-
J4N39_RS07990 (J4N39_08020)	1719542..1719829	-	288	WP_252017846.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J4N39_RS07995 (J4N39_08025)	1719826..1720107	-	282	WP_252017848.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
J4N39_RS08000 (J4N39_08030)	1720289..1721443	+	1155	Protein_1507	IS110 family transposase	-
J4N39_RS08005 (J4N39_08035)	1721934..1722155	+	222	WP_252017850.1	ParD-like family protein	-
J4N39_RS08010 (J4N39_08040)	1722148..1722438	+	291	WP_252017852.1	type II toxin-antitoxin system RelE/ParE family toxin	-
J4N39_RS08015 (J4N39_08045)	1722555..1723160	-	606	WP_252017854.1	hypothetical protein	-
J4N39_RS08020 (J4N39_08050)	1724341..1724694	-	354	WP_252017856.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1707585..1766726	59141
	-	flank	IS/Tn	-	-	1720289..1721443	1154

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10936.64 Da
• Isoelectric Point: 5.1021

>T197041 WP_252017846.1 NZ_CP071848:c1719829-1719542 [Vibrio sp. SCSIO 43136]
MKVVWSPLALQKLGDAAEFISLDNPPAAEKWVNEVFDKTELLGSMPEMGRFVPEMPNTNYREIIFGHYRIIYSLSHEVRI
LTVRNCRQILTEGDV

Nucleotide

• Length: 288 bp

>T197041 NZ_CP095533:2683997-2684173 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTGGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCAAGGGCGACGCAGTGTCATGCCGCGTCACCCCAGTGATGAGATAAAAGAACCATTGCGTAAAGCAATCCTGAAGC
AACTCGGTTTGAGTTAA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10412.89 Da
• Isoelectric Point: 5.1548

>AT197041 WP_252017848.1 NZ_CP071848:c1720107-1719826 [Vibrio sp. SCSIO 43136]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVTN
EDARAQVLGRIKN

Nucleotide

• Length: 282 bp

>AT197041 NZ_CP095533:2684219-2684635 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACAGTTGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCGTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTGCCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGACGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAATTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA