Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 1214400..1214947 Replicon chromosome
Accession NZ_CP071848
Organism Vibrio sp. SCSIO 43136

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J4N39_RS05715 Protein ID WP_252022904.1
Coordinates 1214645..1214947 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J4N39_RS05710 Protein ID WP_252022903.1
Coordinates 1214400..1214657 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4N39_RS05690 (J4N39_05690) 1209500..1210957 - 1458 WP_252022899.1 cardiolipin synthase -
J4N39_RS05695 (J4N39_05695) 1211286..1212620 + 1335 WP_252022900.1 sodium-dependent transporter -
J4N39_RS05700 (J4N39_05700) 1212686..1213384 + 699 WP_252022901.1 TIGR01621 family pseudouridine synthase -
J4N39_RS05705 (J4N39_05705) 1213396..1214337 + 942 WP_252022902.1 class I SAM-dependent methyltransferase -
J4N39_RS05710 (J4N39_05710) 1214400..1214657 + 258 WP_252022903.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J4N39_RS05715 (J4N39_05715) 1214645..1214947 + 303 WP_252022904.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4N39_RS05720 (J4N39_05720) 1214977..1215402 - 426 WP_252022905.1 GspS/AspS pilotin family protein -
J4N39_RS05725 (J4N39_05725) 1215406..1215702 - 297 WP_252022981.1 YciI family protein -
J4N39_RS05730 (J4N39_05730) 1215789..1216184 - 396 WP_252022983.1 acyl-CoA thioester hydrolase YciA -
J4N39_RS05735 (J4N39_05735) 1216251..1216799 - 549 WP_252022985.1 septation protein A -
J4N39_RS05740 (J4N39_05740) 1217122..1217928 - 807 WP_252022987.1 tryptophan synthase subunit alpha -
J4N39_RS05745 (J4N39_05745) 1217928..1219118 - 1191 WP_252022988.1 tryptophan synthase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11569.42 Da        Isoelectric Point: 5.0956

>T197038 WP_252022904.1 NZ_CP071848:1214645-1214947 [Vibrio sp. SCSIO 43136]
MAQIVWTQPALSDLNDIAEYVAIENTLAAKQLVQSIFNAIERLEAFPESGRTPPELPTLPYREVIVSPCRVFYKYDGNSI
YILFVMRQEQDLKRFMLSKK

Download         Length: 303 bp

>T197038 NZ_CP095533:c2411702-2411595 [Escherichia coli]
ATGACGCTCACGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9621.02 Da        Isoelectric Point: 5.6453

>AT197038 WP_252022903.1 NZ_CP071848:1214400-1214657 [Vibrio sp. SCSIO 43136]
MKVELVTSLKREATKILADLHDSKEPVLITEHGKPSAYLVDVDDYESMQKRLAILEGISRGERAIASEQLVSHDEAKDQM
SKWLK

Download         Length: 258 bp

>AT197038 NZ_CP095533:2411750-2411816 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References