Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE(toxin) |
| Location | 1404517..1405076 | Replicon | chromosome |
| Accession | NZ_CP071845 | ||
| Organism | Vibrio sp. SCSIO 43139 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | J4N41_RS06695 | Protein ID | WP_252036435.1 |
| Coordinates | 1404517..1404795 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | J4N41_RS06700 | Protein ID | WP_252036436.1 |
| Coordinates | 1404792..1405076 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J4N41_RS06650 (J4N41_06595) | 1399819..1400214 | + | 396 | WP_252036428.1 | cupin domain-containing protein | - |
| J4N41_RS06655 (J4N41_06600) | 1400355..1400765 | + | 411 | WP_252036429.1 | hypothetical protein | - |
| J4N41_RS06660 (J4N41_06605) | 1400904..1401365 | + | 462 | WP_252036430.1 | DUF1851 domain-containing protein | - |
| J4N41_RS06665 | 1401502..1401687 | + | 186 | WP_252036664.1 | hypothetical protein | - |
| J4N41_RS06670 (J4N41_06610) | 1401654..1401971 | + | 318 | WP_252036431.1 | GNAT family N-acetyltransferase | - |
| J4N41_RS06675 (J4N41_06615) | 1402118..1402549 | + | 432 | WP_252036432.1 | hypothetical protein | - |
| J4N41_RS23355 | 1402587..1402718 | + | 132 | WP_255906341.1 | hypothetical protein | - |
| J4N41_RS06680 (J4N41_06620) | 1402857..1403330 | + | 474 | WP_252036433.1 | GrpB family protein | - |
| J4N41_RS06685 (J4N41_06625) | 1403478..1403894 | + | 417 | WP_252036434.1 | GFA family protein | - |
| J4N41_RS06690 (J4N41_06630) | 1404383..1404487 | + | 105 | WP_252036618.1 | DUF3265 domain-containing protein | - |
| J4N41_RS06695 (J4N41_06635) | 1404517..1404795 | - | 279 | WP_252036435.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| J4N41_RS06700 (J4N41_06640) | 1404792..1405076 | - | 285 | WP_252036436.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| J4N41_RS06705 (J4N41_06645) | 1405755..1406240 | - | 486 | WP_252036437.1 | hypothetical protein | - |
| J4N41_RS06710 (J4N41_06650) | 1406391..1406483 | + | 93 | WP_193837464.1 | DUF3265 domain-containing protein | - |
| J4N41_RS06715 (J4N41_06655) | 1407366..1407515 | + | 150 | WP_252036438.1 | hypothetical protein | - |
| J4N41_RS06720 (J4N41_06660) | 1408024..1408464 | + | 441 | WP_252036439.1 | hypothetical protein | - |
| J4N41_RS06725 (J4N41_06665) | 1409336..1409755 | + | 420 | WP_252036440.1 | lysozyme inhibitor LprI family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1303073..1429922 | 126849 | |
| - | inside | Integron | - | - | 1302066..1428786 | 126720 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10934.60 Da Isoelectric Point: 4.4755
>T197032 WP_252036435.1 NZ_CP071845:c1404795-1404517 [Vibrio sp. SCSIO 43139]
MIFWEEESLNDREKIFEFLYDFNPEAAEKTDEVIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPAS
MIFWEEESLNDREKIFEFLYDFNPEAAEKTDEVIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPAS
Download Length: 279 bp
>T197032 NZ_CP095533:917479-917820 [Escherichia coli]
ATGAAAATTATACCTGCAACGACGCTGCGGGCGACGACGTCATACCTGTCGCCCGTCGTGGTCTGGCAAACATTACTGAC
CCGCCTACTGGAGCAGCACTACGGGCTGAATCTTAATGACACACCATTCAACAATGAAAAGGTGATTCAGGAACACATAG
ACGCCGGGATCACTCTGGTCGATGCCGTCAATTTTCTGGTGGAGAAGTACGAATTGATCCGTATCGACAGGAAAGGATTT
AGCTGGAAGGAACAGACGCCTTATCTTCGTGCGGTCGATATTTTACGGGCGCGACAGGCTACAGGTCTGCTGCGCCGCTG
CCATAACACCACGGCACGGTGA
ATGAAAATTATACCTGCAACGACGCTGCGGGCGACGACGTCATACCTGTCGCCCGTCGTGGTCTGGCAAACATTACTGAC
CCGCCTACTGGAGCAGCACTACGGGCTGAATCTTAATGACACACCATTCAACAATGAAAAGGTGATTCAGGAACACATAG
ACGCCGGGATCACTCTGGTCGATGCCGTCAATTTTCTGGTGGAGAAGTACGAATTGATCCGTATCGACAGGAAAGGATTT
AGCTGGAAGGAACAGACGCCTTATCTTCGTGCGGTCGATATTTTACGGGCGCGACAGGCTACAGGTCTGCTGCGCCGCTG
CCATAACACCACGGCACGGTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10938.31 Da Isoelectric Point: 9.1865
>AT197032 WP_252036436.1 NZ_CP071845:c1405076-1404792 [Vibrio sp. SCSIO 43139]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQVNLAFEKFDLGKANFVDHESAKSR
MAERKAKIRNRGKV
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQVNLAFEKFDLGKANFVDHESAKSR
MAERKAKIRNRGKV
Download Length: 285 bp
>AT197032 NZ_CP095533:917113-917448 [Escherichia coli]
ATGCTGCAAAAGGACAAGGTCATGCAACAAGAATGGGGGCTTCCCTGTACCGTAACACCACGCTTCACTGCTCGACTGGT
ACAGGAAAGACATAACCTGCATTACCTGGCTGATCGGGCCGCAATCACCGGGAAATTCAGCTCCCCGGATCTGCTGCATA
TCGACCAGGCTTTTCCGGTGCTGATGAAACAACTGGAGCTGAAACTGGCTGACGGTGAACTCTCCCCCTGCCAACAACGT
ACCGTCACGCTATACGCCAAAGAACTAACCTGCGAAGCCGATACGCTGGGTTCCAGTGGTTACGTCTATATCGCTATTTA
TCCCGCTCAACGCTGA
ATGCTGCAAAAGGACAAGGTCATGCAACAAGAATGGGGGCTTCCCTGTACCGTAACACCACGCTTCACTGCTCGACTGGT
ACAGGAAAGACATAACCTGCATTACCTGGCTGATCGGGCCGCAATCACCGGGAAATTCAGCTCCCCGGATCTGCTGCATA
TCGACCAGGCTTTTCCGGTGCTGATGAAACAACTGGAGCTGAAACTGGCTGACGGTGAACTCTCCCCCTGCCAACAACGT
ACCGTCACGCTATACGCCAAAGAACTAACCTGCGAAGCCGATACGCTGGGTTCCAGTGGTTACGTCTATATCGCTATTTA
TCCCGCTCAACGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|