Detailed information of TA system TA197032

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1404517..1405076
• Replicon: chromosome
• Accession: NZ_CP071845
• Organism: Vibrio sp. SCSIO 43139

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J4N41_RS06695
• Protein ID: WP_252036435.1
• Coordinates: 1404517..1404795 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: J4N41_RS06700
• Protein ID: WP_252036436.1
• Coordinates: 1404792..1405076 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1303073..1429922	126849
	-	inside	Integron	-	-	1302066..1428786	126720

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-44)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10934.60 Da
• Isoelectric Point: 4.4755

>T197032 WP_252036435.1 NZ_CP071845:c1404795-1404517 [Vibrio sp. SCSIO 43139]
MIFWEEESLNDREKIFEFLYDFNPEAAEKTDEVIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPAS

Nucleotide

• Length: 279 bp

>T197032 NZ_CP095533:917479-917820 [Escherichia coli]
ATGAAAATTATACCTGCAACGACGCTGCGGGCGACGACGTCATACCTGTCGCCCGTCGTGGTCTGGCAAACATTACTGAC
CCGCCTACTGGAGCAGCACTACGGGCTGAATCTTAATGACACACCATTCAACAATGAAAAGGTGATTCAGGAACACATAG
ACGCCGGGATCACTCTGGTCGATGCCGTCAATTTTCTGGTGGAGAAGTACGAATTGATCCGTATCGACAGGAAAGGATTT
AGCTGGAAGGAACAGACGCCTTATCTTCGTGCGGTCGATATTTTACGGGCGCGACAGGCTACAGGTCTGCTGCGCCGCTG
CCATAACACCACGGCACGGTGA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10938.31 Da
• Isoelectric Point: 9.1865

>AT197032 WP_252036436.1 NZ_CP071845:c1405076-1404792 [Vibrio sp. SCSIO 43139]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQVNLAFEKFDLGKANFVDHESAKSR
MAERKAKIRNRGKV

Nucleotide

• Length: 285 bp

>AT197032 NZ_CP095533:917113-917448 [Escherichia coli]
ATGCTGCAAAAGGACAAGGTCATGCAACAAGAATGGGGGCTTCCCTGTACCGTAACACCACGCTTCACTGCTCGACTGGT
ACAGGAAAGACATAACCTGCATTACCTGGCTGATCGGGCCGCAATCACCGGGAAATTCAGCTCCCCGGATCTGCTGCATA
TCGACCAGGCTTTTCCGGTGCTGATGAAACAACTGGAGCTGAAACTGGCTGACGGTGAACTCTCCCCCTGCCAACAACGT
ACCGTCACGCTATACGCCAAAGAACTAACCTGCGAAGCCGATACGCTGGGTTCCAGTGGTTACGTCTATATCGCTATTTA
TCCCGCTCAACGCTGA