Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 80679..81226 Replicon plasmid unnamed
Accession NZ_CP071844
Organism Vibrio sp. SCSIO 43009

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J4N43_RS24255 Protein ID WP_136976192.1
Coordinates 80924..81226 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J4N43_RS24250 Protein ID WP_017634117.1
Coordinates 80679..80936 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4N43_RS24210 (J4N43_24080) 76438..76530 + 93 WP_197072411.1 DUF3265 domain-containing protein -
J4N43_RS24215 (J4N43_24085) 76562..77341 + 780 WP_252094213.1 hypothetical protein -
J4N43_RS24220 (J4N43_24090) 77370..78324 - 955 Protein_79 IS110 family transposase -
J4N43_RS24225 (J4N43_24095) 78668..79243 + 576 WP_252094214.1 hypothetical protein -
J4N43_RS24230 (J4N43_24100) 79361..79756 + 396 WP_252094215.1 DUF3465 domain-containing protein -
J4N43_RS24235 (J4N43_24105) 79949..80203 + 255 WP_017634119.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
J4N43_RS24240 (J4N43_24110) 80196..80465 + 270 WP_005464459.1 Txe/YoeB family addiction module toxin -
J4N43_RS24245 (J4N43_24115) 80508..80597 + 90 WP_081586720.1 DUF3265 domain-containing protein -
J4N43_RS24250 (J4N43_24120) 80679..80936 + 258 WP_017634117.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J4N43_RS24255 (J4N43_24125) 80924..81226 + 303 WP_136976192.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4N43_RS24260 81261..81349 + 89 Protein_87 DUF3265 domain-containing protein -
J4N43_RS24265 (J4N43_24130) 81446..81880 + 435 WP_017634115.1 hypothetical protein -
J4N43_RS24270 (J4N43_24135) 81995..82447 + 453 WP_054579183.1 GIY-YIG nuclease family protein -
J4N43_RS24275 (J4N43_24140) 82673..82969 + 297 WP_053307322.1 YkgJ family cysteine cluster protein -
J4N43_RS24280 (J4N43_24145) 83415..84977 - 1563 WP_025998574.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..135905 135905
- inside Integron - - 71755..80936 9181
- flank IS/Tn - - 77444..78133 689


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11566.49 Da        Isoelectric Point: 5.1765

>T197029 WP_136976192.1 NZ_CP071844:80924-81226 [Vibrio sp. SCSIO 43009]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQAIFSKVERLEAFPESGRIPPELAHLSYREVVVNPCRIFYKQDGDKV
FILFVMRAERDLRKFLLSKQ

Download         Length: 303 bp

>T197029 NZ_CP095529:c4663811-4663626 [Escherichia coli]
GTGAAAAGTGCAGACGTGATCGCTATCCTGAAGCAGCATGGCTGGGAACATATTCGAACCCGTGGCAGTCATCATCAGTT
TCGCCACCCTGTTCATCCGGGTCTGGTGACGGTTCCGCACCCTAAAAAAGATATTAAGCCCGGTACGCTGGCGCAAATTG
GGCGTCAGGCTGGTTTAACATTTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9592.07 Da        Isoelectric Point: 6.7264

>AT197029 WP_017634117.1 NZ_CP071844:80679-80936 [Vibrio sp. SCSIO 43009]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDDAKDKM
SKWLK

Download         Length: 258 bp

>AT197029 NZ_CP095529:c4663609-4663199 [Escherichia coli]
ATGTTTTATCCCGCCTATATCCACAGTGATCCTGACGGCAGCGCCAGCGGTTTTTTCCCTGATGTTCCAGGCTGTTATTT
TGCTGGTGATACGCTGGACAACGCTTTCCAGGATGCGCGAAGTGCACTGGTCGCGCACTTCGAAACCTTATGCGAGATGA
ATGAAGAGTTGCCGCTTCCAGGCTCTGTGGAAACACATCTGGTCCAGCGTGCGCAGGACTTTATTGGCGGGCAATGGTTG
CTGGTGGATATCAATATGAATCAGTTCGAAGGTCGGGCTGAACGTATCAATATTACGATGCCGAAAAGGTTACTGAACAA
GATTGATACCTACGTGCGCAATAACCCAGACTACGCCAACAGAAGTGCGTTTCTGGCAGAAGCTGCCCGGCGTGTATTGC
CGGGCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References