Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2637602..2638167 Replicon chromosome
Accession NZ_CP071826
Organism Burkholderia anthina strain 1CH1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J4G50_RS30815 Protein ID WP_207999375.1
Coordinates 2637796..2638167 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J4G50_RS30810 Protein ID WP_116135619.1
Coordinates 2637602..2637799 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4G50_RS30790 2633891..2636005 - 2115 WP_207999374.1 phospholipase C, phosphocholine-specific -
J4G50_RS30795 2636048..2636251 - 204 WP_175779086.1 hypothetical protein -
J4G50_RS30800 2636587..2636928 - 342 WP_208000570.1 DUF1493 family protein -
J4G50_RS30805 2637291..2637491 - 201 WP_208000583.1 hypothetical protein -
J4G50_RS30810 2637602..2637799 + 198 WP_116135619.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
J4G50_RS30815 2637796..2638167 + 372 WP_207999375.1 PIN domain-containing protein Toxin
J4G50_RS30820 2638233..2640233 - 2001 WP_207999376.1 acetyl-CoA carboxylase biotin carboxylase subunit -
J4G50_RS30825 2640270..2641055 - 786 WP_207999377.1 enoyl-CoA hydratase/isomerase family protein -
J4G50_RS30830 2641075..2642682 - 1608 WP_098551148.1 methylcrotonoyl-CoA carboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(2-44)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13594.73 Da        Isoelectric Point: 5.1363

>T197018 WP_207999375.1 NZ_CP071826:2637796-2638167 [Burkholderia anthina]
MILVDTSVWIDHINAADPMLVALLTEERVLIHPYVVGEISLGSLRNREVVLGALLDLPHAPVATPEETFYLIEREGLFNR
GIGYVDTSLLASARLQPGVTIWTRDKRLKNVADELSLGARLGH

Download         Length: 372 bp

>T197018 NZ_CP095529:c1992820-1992326 [Escherichia coli]
ATGATTCAGGCCCCCGAGCCACTCATGGCAAGGCATCAATTCACCTCTTTTTGCTCGGGAGTAGAAACGATGGATAACTG
GCTAAAGCAGAGAGCCCTAAAAAATCAGCTTGCCGGCGCATCACGTACATTTGTTAGCTGTGATACGTATAGCAACGTTT
TGGCATATTATTCGCTTGCTTCCAGCGCCGTTGAAACGTATGTCGCGACAGGACGATTTCGCCGAAATATGCCAGAACCG
ATCCCTGTTGTAGTACTTGGTCGTCTGGCAATAGATAAATCATTACAGGGTCAGGGCATCGGTCGTGCGATGGTCAGAGA
TGCCGGTCTACGAGTACTACAGGCGGCTGAAGTCATTGGTATTCGCGGAATGTTGGTCCATGCGTTATCAGACCAGGCCC
GTGAGTTTTATCTGCGAGTGGGGTTTGAACCATCGCCTGTCGATTCTATGATACTGATGGCAACATTGGCTGATTTGCAG
GAATGTCTTAAATAG

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7085.19 Da        Isoelectric Point: 10.8072

>AT197018 WP_116135619.1 NZ_CP071826:2637602-2637799 [Burkholderia anthina]
VRTTIALDDDLIAKAQAYTGVEEKSALVREALKALIQREAAKRLANLGGSQPGIKSVPRRRQDVK

Download         Length: 198 bp

>AT197018 NZ_CP095529:c1993110-1992817 [Escherichia coli]
ATGCCAGCAGCCAATAACATTCCAACCAGGCGCGAATCTTTAAATTTGCGCATAAAACCCGCAGAACGCGATCTTATTGA
CCGGGCCGCTAAAGCCCGAGGAAAAAATCGCACCGAATTTGTCCTTGAGGCCGCCAGAGCCGCAGCTGAAGAGGCGCTCA
TTGAGCAGAGAATTTTCAGGATCGATTCTGATGATTACCAGCTATTTTTGAATCGTCTGGATCAGCCCCCCGCGCCCAAT
GCTGCATTACGCAAAACCATGCAAACACCCGCGCCGTGGGAGCAAAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References