Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2355988..2357236 Replicon chromosome
Accession NZ_CP071826
Organism Burkholderia anthina strain 1CH1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J4G50_RS29570 Protein ID WP_207999231.1
Coordinates 2356655..2357236 (+) Length 194 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J4G50_RS29565 Protein ID WP_096501610.1
Coordinates 2355988..2356545 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4G50_RS29540 2351179..2351817 + 639 WP_207999226.1 isochorismatase family protein -
J4G50_RS29545 2351878..2352609 - 732 WP_207999227.1 ribonuclease T2 -
J4G50_RS29550 2352819..2353397 - 579 WP_207999228.1 hypothetical protein -
J4G50_RS29555 2353493..2354896 - 1404 WP_207999229.1 DUF308 domain-containing protein -
J4G50_RS29560 2355278..2355925 + 648 WP_207999230.1 hypothetical protein -
J4G50_RS29565 2355988..2356545 + 558 WP_096501610.1 helix-turn-helix domain-containing protein Antitoxin
J4G50_RS29570 2356655..2357236 + 582 WP_207999231.1 HD domain-containing protein Toxin
J4G50_RS29575 2357962..2360664 + 2703 WP_207999232.1 type VI secretion system tip protein VgrG -
J4G50_RS29580 2360668..2361927 + 1260 WP_207999233.1 VRR-NUC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-169)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 194 a.a.        Molecular weight: 21222.84 Da        Isoelectric Point: 4.9456

>T197017 WP_207999231.1 NZ_CP071826:2356655-2357236 [Burkholderia anthina]
MPLDTLHARLAFLREAERLKDVLRSGHTSSGRPESTAEHSWRLCLMALVFADALPGVDTLKLLKLCVVHDLGEALHGDIP
AIEQAAHPDKSTQERDDLLTLTAGLDRAPRDEIVALWDEYEAAASPEARAAKALDKLETILQHNQGSNPPDFDYAFNLGY
GRRYTDAAPLFAALRTIVDGDTQRRIDARSGDA

Download         Length: 582 bp

>T197017 NZ_CP095529:c1745798-1745412 [Escherichia coli]
ATGGGTGTGTATAAGGCAAGACGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAGGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGTTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAACCAAAGAAATCGAAGATGATGAACTGGCGGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTTTTGATTGAGGTGAAAAATGAGCGATAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20201.27 Da        Isoelectric Point: 10.7101

>AT197017 WP_096501610.1 NZ_CP071826:2355988-2356545 [Burkholderia anthina]
MTPSPLHTPPLGPQLKRWRALRRVKQSHAAELFGVAQSTISRWEAGIQQMSPDERATAERLLAARLDSAGDQALARLIAG
SAGRMHLVCDLTHRLLACSPSRAAEFSQPLPMLLGTSLWRYASPEIVRMEATLDPLGWHDRAGPPSVEFATGANASRVVP
IRGSTCRWTRMMLSDGSAARLVETL

Download         Length: 558 bp

>AT197017 NZ_CP095529:c1745422-1745093 [Escherichia coli]
ATGAGCGATAAATTACAAATGATGCTGGAAGATGCAAAGGAACTGAATGCACTGGGCCTGATGTCTGATAGTGAAGTTGA
TGCCATTGCCGTCATGGTCAAAGCTCGTGAAGTCAGCGCCCGTATAGCCAAAGTCAAATCAATGACGGGTGAAGAGATCA
AAGCCATCCGCACCCGATACGGCATGTCACAATCCGTGCTGGCACATACAATGGGAATGTCAAAAGAAAGTGTCTCGAAA
TGGGAACGAAATGAAATAAAACCGAGCGGCCCGGCACTACGTATTTTGAATACATTGGCAATAAAAGGACCGGAAGTTTT
TGCAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References