Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 733134..733775 Replicon chromosome
Accession NZ_CP071826
Organism Burkholderia anthina strain 1CH1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J4G50_RS22390 Protein ID WP_174926896.1
Coordinates 733437..733775 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag J4G50_RS22385 Protein ID WP_096505596.1
Coordinates 733134..733433 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4G50_RS22360 728315..729586 + 1272 WP_096505602.1 Rieske 2Fe-2S domain-containing protein -
J4G50_RS22365 729601..730077 + 477 WP_014900133.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
J4G50_RS22370 730094..730420 + 327 WP_044847551.1 non-heme iron oxygenase ferredoxin subunit -
J4G50_RS22375 730410..731630 + 1221 WP_208000082.1 FAD-dependent oxidoreductase -
J4G50_RS22380 731799..733085 + 1287 WP_096505598.1 DUF445 domain-containing protein -
J4G50_RS22385 733134..733433 - 300 WP_096505596.1 putative addiction module antidote protein Antitoxin
J4G50_RS22390 733437..733775 - 339 WP_174926896.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4G50_RS22395 734141..735781 + 1641 WP_208000083.1 acetolactate synthase large subunit -
J4G50_RS22400 735810..737243 + 1434 WP_174926897.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-107)

Antitoxin

Uncharacterized protein HI1420

(4-96)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12621.59 Da        Isoelectric Point: 10.2989

>T197010 WP_174926896.1 NZ_CP071826:c733775-733437 [Burkholderia anthina]
MVDILRSMPYSAPTFSIRTTDVFDAWFAGLPDRVARRRIQARIDRLSMGNPGDWKSAGSPIVEMRIDHGPGYRVYYVRRG
TIWVILLCGGAKSTQQADIRAAHAMLARLDLE

Download         Length: 339 bp

>T197010 NZ_CP095529:411315-411488 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTAGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10732.19 Da        Isoelectric Point: 6.9777

>AT197010 WP_096505596.1 NZ_CP071826:c733433-733134 [Burkholderia anthina]
MDKIKTRPWDSAEHLKTDDDMAEYFDACLREAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGTKAHA

Download         Length: 300 bp

>AT197010 NZ_CP095529:410991-411287 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACCGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References