Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1863605..1864139 Replicon chromosome
Accession NZ_CP071825
Organism Burkholderia anthina strain 1CH1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J4G50_RS08815 Protein ID WP_207998584.1
Coordinates 1863605..1863904 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J4G50_RS08820 Protein ID WP_207998585.1
Coordinates 1863894..1864139 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4G50_RS08795 1860439..1861251 + 813 WP_207998677.1 uroporphyrinogen-III C-methyltransferase -
J4G50_RS08800 1861248..1861625 + 378 WP_207998581.1 cobalamin biosynthesis protein -
J4G50_RS08805 1861660..1862262 + 603 WP_207998582.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
J4G50_RS08810 1862266..1863570 + 1305 WP_207998583.1 cobyrinate a,c-diamide synthase -
J4G50_RS08815 1863605..1863904 - 300 WP_207998584.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4G50_RS08820 1863894..1864139 - 246 WP_207998585.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
J4G50_RS08825 1864251..1865414 - 1164 WP_207998586.1 amidohydrolase -
J4G50_RS08830 1865774..1866844 + 1071 WP_207998678.1 hypothetical protein -
J4G50_RS08835 1866813..1867718 + 906 WP_207998587.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
J4G50_RS08840 1867763..1868179 - 417 WP_207998588.1 PIN domain-containing protein -
J4G50_RS08845 1868176..1868442 - 267 WP_096505350.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-94)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11502.10 Da        Isoelectric Point: 6.8436

>T197006 WP_207998584.1 NZ_CP071825:c1863904-1863605 [Burkholderia anthina]
MAVKGRQLQLTPLAELDLEDIWRYTAEHGSLAQADHYHRDLIVTMEALAHGEKVGRACAVREGYFRYAVSSHVVFYRKTD
DTLDVIRIPHQRMDIERHL

Download         Length: 300 bp

>T197006 NZ_CP095526:4897607-4897903 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATACCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATTATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8648.52 Da        Isoelectric Point: 6.7232

>AT197006 WP_207998585.1 NZ_CP071825:c1864139-1863894 [Burkholderia anthina]
MSRNTSVSLGDHFAEFVDSQVQSGRYGSAGDVVRAGLRLLESHETQVRALQEALKAGEASGAPRPFDSEAFLTRMRGSHG
G

Download         Length: 246 bp

>AT197006 NZ_CP095526:4897905-4898300 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References