Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1981261..1981406 Replicon chromosome
Accession NZ_CP071819
Organism Klebsiella pneumoniae subsp. pneumoniae strain 90CM2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1981297..1981399 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1981261..1981406 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IM758_RS09640 1976391..1978451 + 2061 WP_004151449.1 oligopeptidase B -
IM758_RS09645 1978455..1979114 - 660 WP_002911407.1 exodeoxyribonuclease X -
IM758_RS09650 1979193..1979423 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IM758_RS09655 1979536..1979910 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IM758_RS09660 1979914..1980783 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
IM758_RS09665 1980800..1981138 + 339 WP_002911404.1 YebY family protein -
- 1981261..1981406 - 146 - - Antitoxin
- 1981297..1981399 + 103 - - Toxin
IM758_RS09670 1981774..1981917 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IM758_RS09675 1982022..1982990 - 969 WP_074442383.1 VirK/YbjX family protein -
IM758_RS09680 1983147..1983800 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
IM758_RS09685 1983797..1983988 - 192 WP_002911395.1 YebW family protein -
IM758_RS09690 1984086..1984325 - 240 WP_002911393.1 YebV family protein -
IM758_RS09695 1984441..1985874 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T196983 NZ_CP071819:1981297-1981399 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT196983 NZ_CP071819:c1981406-1981261 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References