Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2971110..2971779 Replicon chromosome
Accession NZ_CP071802
Organism Yersinia ruckeri strain KMM821

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag YR821_RS13600 Protein ID WP_038241020.1
Coordinates 2971110..2971532 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag YR821_RS13605 Protein ID WP_004719196.1
Coordinates 2971513..2971779 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YR821_RS13580 (YR821_2818) 2966949..2968682 - 1734 WP_004719191.1 single-stranded-DNA-specific exonuclease RecJ -
YR821_RS13585 (YR821_2819) 2968689..2969405 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
YR821_RS13590 (YR821_2820) 2969437..2970336 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
YR821_RS13595 (YR821_2821) 2970444..2970962 + 519 WP_038241022.1 flavodoxin FldB -
YR821_RS13600 (YR821_2822) 2971110..2971532 - 423 WP_038241020.1 protein YgfX Toxin
YR821_RS13605 (YR821_2823) 2971513..2971779 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
YR821_RS13610 (YR821_2824) 2972073..2973065 + 993 WP_038241018.1 tRNA-modifying protein YgfZ -
YR821_RS13615 (YR821_2825) 2973204..2973878 - 675 WP_049687854.1 hemolysin III family protein -
YR821_RS13620 2974186..2974442 + 257 Protein_2649 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T196963 WP_038241020.1 NZ_CP071802:c2971532-2971110 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

>T196963 NZ_CP095519:16976-17125 [Escherichia coli]
ATGACGAAATATACCCTTATCGGGTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAGCTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT196963 WP_004719196.1 NZ_CP071802:c2971779-2971513 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT196963 NZ_CP095519:c16928-16872 [Escherichia coli]
GTACTTCATGCAGGCCTCACGAGTTAATGGATTAACAAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References