Detailed information of TA system TA196949

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 5540788..5541293
• Replicon: chromosome
• Accession: NZ_CP071797
• Organism: Pseudomonas fluorescens strain YK-310

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JZM58_RS24560
• Protein ID: WP_207983876.1
• Coordinates: 5541039..5541293 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: JZM58_RS24555
• Protein ID: WP_207983875.1
• Coordinates: 5540788..5541042 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JZM58_RS24530 (JZM58_24530)	5536108..5536473	+	366	WP_207983872.1	hypothetical protein	-
JZM58_RS24535 (JZM58_24535)	5536498..5537190	-	693	WP_243459111.1	hypothetical protein	-
JZM58_RS24540 (JZM58_24540)	5537366..5537719	+	354	WP_064383933.1	hypothetical protein	-
JZM58_RS24545 (JZM58_24545)	5537853..5538599	+	747	WP_207983873.1	hypothetical protein	-
JZM58_RS24550 (JZM58_24550)	5538671..5540590	+	1920	WP_207983874.1	alkaline phosphatase D family protein	-
JZM58_RS24555 (JZM58_24555)	5540788..5541042	+	255	WP_207983875.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
JZM58_RS24560 (JZM58_24560)	5541039..5541293	+	255	WP_207983876.1	Txe/YoeB family addiction module toxin	Toxin
JZM58_RS24565 (JZM58_24565)	5541302..5542474	-	1173	WP_207983877.1	aspartate aminotransferase family protein	-
JZM58_RS24570 (JZM58_24570)	5542577..5543482	+	906	WP_064599264.1	LysR family transcriptional regulator	-
JZM58_RS24575 (JZM58_24575)	5543528..5543932	+	405	WP_207983878.1	GNAT family N-acetyltransferase	-
JZM58_RS24580 (JZM58_24580)	5543997..5544521	+	525	WP_207983879.1	hypothetical protein	-
JZM58_RS24585 (JZM58_24585)	5544695..5545399	+	705	WP_207983880.1	hypothetical protein	-
JZM58_RS24590 (JZM58_24590)	5545469..5545960	-	492	WP_007956714.1	RidA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9980.57 Da
• Isoelectric Point: 8.5103

>T196949 WP_207983876.1 NZ_CP071797:5541039-5541293 [Pseudomonas fluorescens]
MKIQFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRQITAEHRLVYAIVDDEICVITC
RFHY

Nucleotide

• Length: 255 bp

>T196949 NZ_CP095518:1643466-1643840 [Escherichia coli]
ATGAACACATTACCCGATACACACATACGGGAGGCATCGCATTGCCAGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACTCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9467.89 Da
• Isoelectric Point: 5.1314

>AT196949 WP_207983875.1 NZ_CP071797:5540788-5541042 [Pseudomonas fluorescens]
MDTINYTTARAHLAETMDRVNEDCTPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGEMRAGKAKVRQ
LIEE

Nucleotide

• Length: 255 bp

>AT196949 NZ_CP095518:1643008-1643376 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA