Detailed information of TA system TA196948

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3836833..3837301
• Replicon: chromosome
• Accession: NZ_CP071797
• Organism: Pseudomonas fluorescens strain YK-310

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JZM58_RS16895
• Protein ID: WP_243459157.1
• Coordinates: 3837074..3837301 (+)
• Length: 76 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JZM58_RS16890
• Protein ID: WP_085730699.1
• Coordinates: 3836833..3837027 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JZM58_RS29220	3832341..3832478	-	138	Protein_3334	metal ABC transporter ATP-binding protein	-
JZM58_RS16870 (JZM58_16870)	3832456..3833424	-	969	WP_207982950.1	Gfo/Idh/MocA family oxidoreductase	-
JZM58_RS16875 (JZM58_16875)	3833442..3834329	-	888	WP_207982951.1	Dyp-type peroxidase	-
JZM58_RS16880 (JZM58_16880)	3834386..3835420	-	1035	WP_207982953.1	AraC family transcriptional regulator	-
JZM58_RS16885 (JZM58_16885)	3835632..3836579	+	948	WP_207982954.1	transporter	-
JZM58_RS16890 (JZM58_16890)	3836833..3837027	+	195	WP_085730699.1	stability determinant	Antitoxin
JZM58_RS16895 (JZM58_16895)	3837074..3837301	+	228	WP_243459157.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Putative toxin of bacterial toxin-antitoxin pair (1-85)

Antitoxin

• GNAT domain (18-121)

Sequences

Toxin

Protein

• Length: 76 a.a.
• Molecular weight: 8474.66 Da
• Isoelectric Point: 11.4092

>T196948 WP_243459157.1 NZ_CP071797:3837074-3837301 [Pseudomonas fluorescens]
IEQYNSNASTALQHKVGAATQRLSSIPYGYRSGRAPGTREMVVNPNYLLVYRVNGRIKILTLVHTRRQYPRTSSP

Nucleotide

• Length: 228 bp

>T196948 NZ_CP095518:1346974-1347231 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7573.51 Da
• Isoelectric Point: 5.6939

>AT196948 WP_085730699.1 NZ_CP071797:3836833-3837027 [Pseudomonas fluorescens]
MSILHSPFYADFESEEEAESYDRWFRAKVQAVLDDPRPGIPHKEAMVRLDQLLEERRKNRRAAA

Nucleotide

• Length: 195 bp

>AT196948 NZ_CP095518:1347243-1347788 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA