Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2505020..2505485 Replicon chromosome
Accession NZ_CP071797
Organism Pseudomonas fluorescens strain YK-310

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JZM58_RS11305 Protein ID WP_179695643.1
Coordinates 2505020..2505289 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JZM58_RS11310 Protein ID WP_243459133.1
Coordinates 2505279..2505485 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JZM58_RS11260 (JZM58_11260) 2500028..2500501 + 474 WP_007956136.1 type II secretion system protein -
JZM58_RS11265 (JZM58_11265) 2500507..2500881 + 375 WP_007956137.1 type II secretion system protein -
JZM58_RS11270 (JZM58_11270) 2500856..2501407 + 552 WP_207985653.1 type II secretion system protein -
JZM58_RS11275 (JZM58_11275) 2501404..2501796 + 393 WP_207985654.1 curli production assembly/transport protein CsgE -
JZM58_RS11280 (JZM58_11280) 2501793..2502224 + 432 WP_007956141.1 curli assembly protein CsgF -
JZM58_RS11285 (JZM58_11285) 2502254..2503114 + 861 WP_207985655.1 CsgG/HfaB family protein -
JZM58_RS11290 (JZM58_11290) 2503299..2503589 - 291 WP_207985656.1 hypothetical protein -
JZM58_RS11295 (JZM58_11295) 2503964..2504335 + 372 WP_207985657.1 hypothetical protein -
JZM58_RS29170 2504372..2504506 + 135 Protein_2227 CopG family transcriptional regulator -
JZM58_RS11300 (JZM58_11300) 2504584..2504811 + 228 WP_207985658.1 antitoxin -
JZM58_RS11305 (JZM58_11305) 2505020..2505289 - 270 WP_179695643.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JZM58_RS11310 (JZM58_11310) 2505279..2505485 - 207 WP_243459133.1 antitoxin Antitoxin
JZM58_RS11315 (JZM58_11315) 2505756..2507207 - 1452 WP_207985659.1 curlin -
JZM58_RS11320 (JZM58_11320) 2507234..2507698 - 465 WP_007956150.1 curlin -
JZM58_RS11325 (JZM58_11325) 2507798..2510032 - 2235 WP_207985660.1 Ig-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10204.76 Da        Isoelectric Point: 9.4341

>T196947 WP_179695643.1 NZ_CP071797:c2505289-2505020 [Pseudomonas fluorescens]
MQVEWQPEARAELLHILDYISDRNFKAANKLSNAIEAATVTLTKHPHLYRVGRTPGTREMVVHPNYLLIYQAVGRINILG
VVHARQEYP

Download         Length: 270 bp

>T196947 NZ_CP095518:1295980-1296321 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCATGTCACCGTCGGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CTGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGAGGAGAGCGAA
CTGATGCAGTCGCTACGCCAGGTGTGCAAACTGTCGGCGCGTAAACAAAAGCAGGTGCAGGCGTTTATTGGAGTGATTGC
CGGTAAACAGAAAGTCGCGTAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7583.72 Da        Isoelectric Point: 4.4278

>AT196947 WP_243459133.1 NZ_CP071797:c2505485-2505279 [Pseudomonas fluorescens]
MIDPSLIDPLCPVVSDLAPEEQAASYDRWLIAKIQASMNDPRPSIPNDQVMAEMHALMEAKRKKYDAG

Download         Length: 207 bp

>AT196947 NZ_CP095518:c1295985-1295909 [Escherichia coli]
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCAGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References