Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
Location | 3823728..3825244 | Replicon | chromosome |
Accession | NZ_CP071796 | ||
Organism | Ottowia testudinis strain 27C |
Toxin (Protein)
Gene name | rlegT | Uniprot ID | - |
Locus tag | J1M35_RS18125 | Protein ID | WP_208008668.1 |
Coordinates | 3823728..3824648 (-) | Length | 307 a.a. |
Antitoxin (Protein)
Gene name | rlegA | Uniprot ID | - |
Locus tag | J1M35_RS18130 | Protein ID | WP_208008672.1 |
Coordinates | 3824645..3825244 (-) | Length | 200 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
J1M35_RS18110 (J1M35_18110) | 3819538..3820245 | + | 708 | WP_208008662.1 | Crp/Fnr family transcriptional regulator | - |
J1M35_RS18115 (J1M35_18115) | 3820414..3821244 | + | 831 | WP_208008664.1 | pseudouridine synthase | - |
J1M35_RS18120 (J1M35_18120) | 3821433..3823508 | + | 2076 | WP_208008666.1 | molecular chaperone HtpG | - |
J1M35_RS18125 (J1M35_18125) | 3823728..3824648 | - | 921 | WP_208008668.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
J1M35_RS18130 (J1M35_18130) | 3824645..3825244 | - | 600 | WP_208008672.1 | AbiEi antitoxin N-terminal domain-containing protein | Antitoxin |
J1M35_RS18135 (J1M35_18135) | 3825373..3826722 | - | 1350 | WP_208008673.1 | heavy metal sensor histidine kinase | - |
J1M35_RS18140 (J1M35_18140) | 3826719..3827408 | - | 690 | WP_208008675.1 | heavy metal response regulator transcription factor | - |
J1M35_RS18145 (J1M35_18145) | 3827536..3829401 | + | 1866 | WP_208008682.1 | copper resistance system multicopper oxidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 307 a.a. Molecular weight: 34140.35 Da Isoelectric Point: 7.9067
>T196941 WP_208008668.1 NZ_CP071796:c3824648-3823728 [Ottowia testudinis]
MTQKGAIRNSAASVRARLLNKARAERLDFNLLLTRYALERILYRLSVSEQSGHFLLKGALLFDLWFDLPHRPTHDADLLG
FGSTDIPYLENLFREISQIASDDGIVFQASSVKAAEIRKEANYVGVRVTMLGLLDGARCPVQIDIGFGDAVTPAPENVRY
PVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGMLNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFERRGTAIPPGTPLG
LNDEFALDEQKAKQWQAFQRKNALESIPLPAVIVELRKWLMPVLTALATESGCTHQWRAGKGWSES
MTQKGAIRNSAASVRARLLNKARAERLDFNLLLTRYALERILYRLSVSEQSGHFLLKGALLFDLWFDLPHRPTHDADLLG
FGSTDIPYLENLFREISQIASDDGIVFQASSVKAAEIRKEANYVGVRVTMLGLLDGARCPVQIDIGFGDAVTPAPENVRY
PVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGMLNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFERRGTAIPPGTPLG
LNDEFALDEQKAKQWQAFQRKNALESIPLPAVIVELRKWLMPVLTALATESGCTHQWRAGKGWSES
Download Length: 921 bp
>T196941 NZ_CP095516:5938-6453 [Escherichia coli]
ATGAAATTTTACACTATATCAAGCAGATACATTGAATACCTAAAGGGATTCGAAGACAAAGTTCCCAATAGCGAAGATCC
TAACTATCAGAATCCGAAAGCTTTCATTGGCATTGTGTTAGAGATTCAAGGGCATAAGTATCTAGCCCCTTTAACATCCC
CAAAGCCATGGCATAGCACTATTAAAGAATCATCGCCTAGCTTCTTTAAGCTCCATGAAAATGGTGTCCCCGAAAATCAG
CTCGGATTGATTAATCTGAAGTTCATGATTCCAATCATCGAAGCCGAAGTATCCTTACTTGACTTGAACGGTATGCCGAA
TACCGCCTACAAGAGAATGCTCTATAAGCAGCTCCAGTTTATTCGTGTAAATTCAGACAAAATAGCTGAGAAATCAGAGC
TTTTAAGGAAGCTCGTCCTGCAAGGAAAAATGCAAGGAACATGTAATTTTTCCCTGTTAGAAGAAAAATACCGAGATTTC
GGCAAAGAAGCTAATGACACGGAAGAAGGCGAGTAA
ATGAAATTTTACACTATATCAAGCAGATACATTGAATACCTAAAGGGATTCGAAGACAAAGTTCCCAATAGCGAAGATCC
TAACTATCAGAATCCGAAAGCTTTCATTGGCATTGTGTTAGAGATTCAAGGGCATAAGTATCTAGCCCCTTTAACATCCC
CAAAGCCATGGCATAGCACTATTAAAGAATCATCGCCTAGCTTCTTTAAGCTCCATGAAAATGGTGTCCCCGAAAATCAG
CTCGGATTGATTAATCTGAAGTTCATGATTCCAATCATCGAAGCCGAAGTATCCTTACTTGACTTGAACGGTATGCCGAA
TACCGCCTACAAGAGAATGCTCTATAAGCAGCTCCAGTTTATTCGTGTAAATTCAGACAAAATAGCTGAGAAATCAGAGC
TTTTAAGGAAGCTCGTCCTGCAAGGAAAAATGCAAGGAACATGTAATTTTTCCCTGTTAGAAGAAAAATACCGAGATTTC
GGCAAAGAAGCTAATGACACGGAAGAAGGCGAGTAA
Antitoxin
Download Length: 200 a.a. Molecular weight: 21763.40 Da Isoelectric Point: 9.9325
>AT196941 WP_208008672.1 NZ_CP071796:c3825244-3824645 [Ottowia testudinis]
MATTTQKLLDCANARGLVRSVDLAQHGIPRIALTRAVQRGQLERVGRGVYALPGRAVSAHSSLAEVALRVPKGVVCLLSA
LRLHELTTQAPFEVWLAIDNKAGTPKLDYPPLRIVRFSGAALIGGVEEHVVDGVIVRVTGVAKTVADCFKYRNKIGLDVA
LEALREAWDAKRMSSDEIWHYAKICRVANVMRPYLESLT
MATTTQKLLDCANARGLVRSVDLAQHGIPRIALTRAVQRGQLERVGRGVYALPGRAVSAHSSLAEVALRVPKGVVCLLSA
LRLHELTTQAPFEVWLAIDNKAGTPKLDYPPLRIVRFSGAALIGGVEEHVVDGVIVRVTGVAKTVADCFKYRNKIGLDVA
LEALREAWDAKRMSSDEIWHYAKICRVANVMRPYLESLT
Download Length: 600 bp
>AT196941 NZ_CP095516:5796-5888 [Escherichia coli]
AGGTGATTTGCTACCTTTAAGTGCAGCTAGAAATTCAGGTGATTTGCTACCTTAAGTGCAGCTAGAAATTTAGGTCATTT
ACTACCTTAAAGT
AGGTGATTTGCTACCTTTAAGTGCAGCTAGAAATTCAGGTGATTTGCTACCTTAAGTGCAGCTAGAAATTTAGGTCATTT
ACTACCTTAAAGT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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