196941

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3823728..3825244 Replicon chromosome
Accession NZ_CP071796
Organism Ottowia testudinis strain 27C

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag J1M35_RS18125 Protein ID WP_208008668.1
Coordinates 3823728..3824648 (-) Length 307 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag J1M35_RS18130 Protein ID WP_208008672.1
Coordinates 3824645..3825244 (-) Length 200 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1M35_RS18110 (J1M35_18110) 3819538..3820245 + 708 WP_208008662.1 Crp/Fnr family transcriptional regulator -
J1M35_RS18115 (J1M35_18115) 3820414..3821244 + 831 WP_208008664.1 pseudouridine synthase -
J1M35_RS18120 (J1M35_18120) 3821433..3823508 + 2076 WP_208008666.1 molecular chaperone HtpG -
J1M35_RS18125 (J1M35_18125) 3823728..3824648 - 921 WP_208008668.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
J1M35_RS18130 (J1M35_18130) 3824645..3825244 - 600 WP_208008672.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
J1M35_RS18135 (J1M35_18135) 3825373..3826722 - 1350 WP_208008673.1 heavy metal sensor histidine kinase -
J1M35_RS18140 (J1M35_18140) 3826719..3827408 - 690 WP_208008675.1 heavy metal response regulator transcription factor -
J1M35_RS18145 (J1M35_18145) 3827536..3829401 + 1866 WP_208008682.1 copper resistance system multicopper oxidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 307 a.a.        Molecular weight: 34140.35 Da        Isoelectric Point: 7.9067

>T196941 WP_208008668.1 NZ_CP071796:c3824648-3823728 [Ottowia testudinis]
MTQKGAIRNSAASVRARLLNKARAERLDFNLLLTRYALERILYRLSVSEQSGHFLLKGALLFDLWFDLPHRPTHDADLLG
FGSTDIPYLENLFREISQIASDDGIVFQASSVKAAEIRKEANYVGVRVTMLGLLDGARCPVQIDIGFGDAVTPAPENVRY
PVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGMLNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFERRGTAIPPGTPLG
LNDEFALDEQKAKQWQAFQRKNALESIPLPAVIVELRKWLMPVLTALATESGCTHQWRAGKGWSES

Download         Length: 921 bp

>T196941 NZ_CP095516:5938-6453 [Escherichia coli]
ATGAAATTTTACACTATATCAAGCAGATACATTGAATACCTAAAGGGATTCGAAGACAAAGTTCCCAATAGCGAAGATCC
TAACTATCAGAATCCGAAAGCTTTCATTGGCATTGTGTTAGAGATTCAAGGGCATAAGTATCTAGCCCCTTTAACATCCC
CAAAGCCATGGCATAGCACTATTAAAGAATCATCGCCTAGCTTCTTTAAGCTCCATGAAAATGGTGTCCCCGAAAATCAG
CTCGGATTGATTAATCTGAAGTTCATGATTCCAATCATCGAAGCCGAAGTATCCTTACTTGACTTGAACGGTATGCCGAA
TACCGCCTACAAGAGAATGCTCTATAAGCAGCTCCAGTTTATTCGTGTAAATTCAGACAAAATAGCTGAGAAATCAGAGC
TTTTAAGGAAGCTCGTCCTGCAAGGAAAAATGCAAGGAACATGTAATTTTTCCCTGTTAGAAGAAAAATACCGAGATTTC
GGCAAAGAAGCTAATGACACGGAAGAAGGCGAGTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 21763.40 Da        Isoelectric Point: 9.9325

>AT196941 WP_208008672.1 NZ_CP071796:c3825244-3824645 [Ottowia testudinis]
MATTTQKLLDCANARGLVRSVDLAQHGIPRIALTRAVQRGQLERVGRGVYALPGRAVSAHSSLAEVALRVPKGVVCLLSA
LRLHELTTQAPFEVWLAIDNKAGTPKLDYPPLRIVRFSGAALIGGVEEHVVDGVIVRVTGVAKTVADCFKYRNKIGLDVA
LEALREAWDAKRMSSDEIWHYAKICRVANVMRPYLESLT

Download         Length: 600 bp

>AT196941 NZ_CP095516:5796-5888 [Escherichia coli]
AGGTGATTTGCTACCTTTAAGTGCAGCTAGAAATTCAGGTGATTTGCTACCTTAAGTGCAGCTAGAAATTTAGGTCATTT
ACTACCTTAAAGT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References