Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 2569234..2569742 Replicon chromosome
Accession NZ_CP071796
Organism Ottowia testudinis strain 27C

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag J1M35_RS12045 Protein ID WP_208007284.1
Coordinates 2569234..2569491 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J1M35_RS12050 Protein ID WP_208007285.1
Coordinates 2569488..2569742 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1M35_RS12015 (J1M35_12015) 2564602..2565210 + 609 WP_208007278.1 Maf family nucleotide pyrophosphatase -
J1M35_RS12020 (J1M35_12020) 2565207..2565974 + 768 WP_208007279.1 SAM-dependent methyltransferase -
J1M35_RS12025 (J1M35_12025) 2566111..2567067 - 957 WP_208007280.1 S49 family peptidase -
J1M35_RS12030 (J1M35_12030) 2567229..2567606 - 378 WP_208007281.1 Rieske 2Fe-2S domain-containing protein -
J1M35_RS12035 (J1M35_12035) 2567638..2568300 - 663 WP_208007282.1 HAD-IA family hydrolase -
J1M35_RS12040 (J1M35_12040) 2568297..2569244 - 948 WP_208007283.1 RluA family pseudouridine synthase -
J1M35_RS12045 (J1M35_12045) 2569234..2569491 - 258 WP_208007284.1 Txe/YoeB family addiction module toxin Toxin
J1M35_RS12050 (J1M35_12050) 2569488..2569742 - 255 WP_208007285.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J1M35_RS12055 (J1M35_12055) 2569938..2570273 + 336 WP_208007286.1 hypothetical protein -
J1M35_RS12060 (J1M35_12060) 2570427..2573309 + 2883 WP_208007287.1 Rne/Rng family ribonuclease -
J1M35_RS12065 (J1M35_12065) 2573604..2574509 + 906 WP_208007288.1 M23 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10063.20 Da        Isoelectric Point: 4.8013

>T196940 WP_208007284.1 NZ_CP071796:c2569491-2569234 [Ottowia testudinis]
MIVFEGAGWDDYLSWQQNDRQVLRKINQLIHDIQRDPWSGLGKPEALKDNLAGFWSRRITDEHRIVYRIEDDDLIVAQCR
GHNDD

Download         Length: 258 bp

>T196940 NZ_CP095515:c87984-87679 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTTCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCCCGCCTGCTGTCAGACAAAGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGTCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9822.32 Da        Isoelectric Point: 9.8815

>AT196940 WP_208007285.1 NZ_CP071796:c2569742-2569488 [Ottowia testudinis]
MQAITYSEARNNLAKHLDRVVNDCDFTVITRQKGEATVLMSLREFESWKETMFLLRGKNGPRLLKSVANIRNRENLVKRE
LIDE

Download         Length: 255 bp

>AT196940 NZ_CP095515:c88204-87986 [Escherichia coli]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAATTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGATGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References