Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1027118..1027665 Replicon chromosome
Accession NZ_CP071795
Organism Polaribacter batillariae strain G4M1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JL193_RS04550 Protein ID WP_207972686.1
Coordinates 1027366..1027665 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag JL193_RS04545 Protein ID WP_207973382.1
Coordinates 1027118..1027366 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL193_RS04510 (JL193_04510) 1023006..1023596 - 591 WP_207972684.1 hypothetical protein -
JL193_RS04515 (JL193_04515) 1023784..1024542 + 759 WP_207972685.1 helix-turn-helix transcriptional regulator -
JL193_RS04520 (JL193_04520) 1024543..1025265 - 723 WP_207973380.1 ThiF family adenylyltransferase -
JL193_RS04525 (JL193_04525) 1025271..1025891 - 621 WP_207973381.1 IS630 family transposase -
JL193_RS04530 (JL193_04530) 1025836..1026339 - 504 WP_207970603.1 helix-turn-helix domain-containing protein -
JL193_RS04545 (JL193_04545) 1027118..1027366 + 249 WP_207973382.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
JL193_RS04550 (JL193_04550) 1027366..1027665 + 300 WP_207972686.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JL193_RS04555 (JL193_04555) 1027872..1028117 + 246 Protein_902 transposase -
JL193_RS04560 (JL193_04560) 1028633..1029697 + 1065 WP_207972688.1 chorismate synthase -
JL193_RS04565 (JL193_04565) 1030070..1031098 - 1029 WP_207972689.1 phytase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-75)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12300.90 Da        Isoelectric Point: 7.1995

>T196933 WP_207972686.1 NZ_CP071795:1027366-1027665 [Polaribacter batillariae]
MEYKISQEANRDIENIWLYTFENWSAEQADRYFNLILDEIEYIAKNPTSGKDYNEIRKGYYRSRIKSHFIFYKINRKKER
VEIIRILHQRMDIESRLDE

Download         Length: 300 bp

>T196933 NZ_CP095514:c3063538-3063287 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9464.95 Da        Isoelectric Point: 10.1540

>AT196933 WP_207973382.1 NZ_CP071795:1027118-1027366 [Polaribacter batillariae]
MPKNTSILLGDYFDKFISQQIKSGKYSSASEVVRAALRMFEHQESKKSELIKALKKGEKSGFVENLDRTKLLKEIHQKYL
TE

Download         Length: 249 bp

>AT196933 NZ_CP095514:c3063290-3063036 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References