Detailed information of TA system TA196930

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 5758246..5758901
• Replicon: chromosome
• Accession: NZ_CP071793
• Organism: Sulfidibacter corallicola strain M133

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: J3U87_RS17595
• Protein ID: WP_272932499.1
• Coordinates: 5758246..5758665 (-)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: J3U87_RS17600
• Protein ID: WP_237384366.1
• Coordinates: 5758662..5758901 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J3U87_RS17580 (J3U87_17610)	5756934..5757257	-	324	WP_237384362.1	RHS repeat domain-containing protein	-
J3U87_RS17585 (J3U87_17615)	5757558..5757818	+	261	WP_237384363.1	type II toxin-antitoxin system VapB family antitoxin	-
J3U87_RS17590 (J3U87_17620)	5757827..5758213	+	387	WP_237384364.1	type II toxin-antitoxin system VapC family toxin	-
J3U87_RS17595 (J3U87_17625)	5758246..5758665	-	420	WP_272932499.1	type II toxin-antitoxin system VapC family toxin	Toxin
J3U87_RS17600 (J3U87_17630)	5758662..5758901	-	240	WP_237384366.1	TraY domain-containing protein	Antitoxin
J3U87_RS17605 (J3U87_17635)	5759627..5760091	-	465	WP_237384367.1	hotdog fold domain-containing protein	-
J3U87_RS17610 (J3U87_17640)	5760291..5761643	-	1353	WP_237384368.1	DUF1501 domain-containing protein	-
J3U87_RS17615 (J3U87_17645)	5761679..5763514	-	1836	WP_237384369.1	DUF1549 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

• Relaxosome protein TraY (9-37)

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 15211.68 Da
• Isoelectric Point: 7.4038

>T196930 WP_272932499.1 NZ_CP071793:c5758665-5758246 [Sulfidibacter corallicola]
MIILDTNVVSEPMKPTGNPVVQAWLDQQVAESLFLTTISLSELLVGIEILPESKRKQGLSHALRELLHHLFGSRILSFDE
KAAIAYASMFRRARTLGKAISMADGQIAAITKVHGFTVATRDTSPFEAAGIPVIDPWKT

Nucleotide

• Length: 420 bp

>T196930 NZ_CP095514:c2761677-2761575 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8946.13 Da
• Isoelectric Point: 5.1898

>AT196930 WP_237384366.1 NZ_CP071793:c5758901-5758662 [Sulfidibacter corallicola]
MAAVTVRNLPEETHRALKLRAARNGRSTEAEIRVILEEAVRPKERIKIGSQLAAFAQQYEGLELETNRDQAPMEPAEFE

Nucleotide

• Length: 240 bp

>AT196930 NZ_CP095514:2761537-2761805 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT