Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5757558..5758213 Replicon chromosome
Accession NZ_CP071793
Organism Sulfidibacter corallicola strain M133

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J3U87_RS17590 Protein ID WP_237384364.1
Coordinates 5757827..5758213 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J3U87_RS17585 Protein ID WP_237384363.1
Coordinates 5757558..5757818 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3U87_RS17580 (J3U87_17610) 5756934..5757257 - 324 WP_237384362.1 RHS repeat domain-containing protein -
J3U87_RS17585 (J3U87_17615) 5757558..5757818 + 261 WP_237384363.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
J3U87_RS17590 (J3U87_17620) 5757827..5758213 + 387 WP_237384364.1 type II toxin-antitoxin system VapC family toxin Toxin
J3U87_RS17595 (J3U87_17625) 5758246..5758665 - 420 WP_272932499.1 type II toxin-antitoxin system VapC family toxin -
J3U87_RS17600 (J3U87_17630) 5758662..5758901 - 240 WP_237384366.1 TraY domain-containing protein -
J3U87_RS17605 (J3U87_17635) 5759627..5760091 - 465 WP_237384367.1 hotdog fold domain-containing protein -
J3U87_RS17610 (J3U87_17640) 5760291..5761643 - 1353 WP_237384368.1 DUF1501 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin

SpoVT-AbrB domain

(8-54)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14295.72 Da        Isoelectric Point: 6.4719

>T196929 WP_237384364.1 NZ_CP071793:5757827-5758213 [Sulfidibacter corallicola]
MLDTNTVSYLMRGDIGVAKKVRNIPMDAVCISVITEAELLYGLAKRSSGGRLRELVKRLLDRIDVLPWDREVAIRFGDLR
AHLERKGMTLGPLDMQIAAHALAEAAVLVTNDRAFLQVPELEIENWVA

Download         Length: 387 bp

>T196929 NZ_CP095514:c2468561-2467239 [Escherichia coli]
ATGCCTAAACTAGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCTGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGATAGCGTTGGTGCCGTGACGTTAATCCCCGAAGA
TGAAACCGTAACGTGTCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGTTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACTGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAGGGAATAACGCCAACGACGCACATTATCAAATTGCCGATTGGCGAAAT
CAGACAGCCCAATGCGACGCTCGATCTTAGCCAAAGCGTTGATAATGAGTATTACTGTTTGCTGCTGGCGAAAGAACTCG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCAAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGCCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCCGGTATCGCGCAAATTATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTCTTCCAGTGGTTGATTGGCGCAACAGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGGCTCACACCATTTTATGACATCATTTCGGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGAATTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGGTCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9984.18 Da        Isoelectric Point: 4.6812

>AT196929 WP_237384363.1 NZ_CP071793:5757558-5757818 [Sulfidibacter corallicola]
MTQTAKLFMNGRSQAVRLPAAFRFEGKEVFIRRDPETGDVILSRKPVSWDGFFELLGEVEVPRDFLDPADREQGTHDRDP
FDGWRE

Download         Length: 261 bp

>AT196929 NZ_CP095514:c2468827-2468561 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAACGGCTGGAC
GCAGAGCGAGTTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAATCCTGACAATACCTCGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAAGCA
GCAGAACAGCAAGATTTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References