Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4596682..4597229 Replicon chromosome
Accession NZ_CP071785
Organism Marinobacter sp. CA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J2887_RS20985 Protein ID WP_227173067.1
Coordinates 4596927..4597229 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J2887_RS20980 Protein ID WP_227173066.1
Coordinates 4596682..4596939 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J2887_RS20955 (J2887_20895) 4592274..4593212 + 939 WP_227173062.1 IS30 family transposase -
J2887_RS20960 (J2887_20900) 4593219..4593755 + 537 Protein_4105 transposase -
J2887_RS20965 (J2887_20905) 4594212..4595165 - 954 WP_227173063.1 IS110 family transposase -
J2887_RS20970 (J2887_20910) 4595439..4595798 + 360 WP_227173064.1 hypothetical protein -
J2887_RS20975 (J2887_20915) 4595869..4596345 + 477 WP_227173065.1 hypothetical protein -
J2887_RS20980 (J2887_20920) 4596682..4596939 + 258 WP_227173066.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J2887_RS20985 (J2887_20925) 4596927..4597229 + 303 WP_227173067.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J2887_RS20990 (J2887_20930) 4597379..4597621 + 243 WP_075878843.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
J2887_RS20995 (J2887_20935) 4597618..4597881 + 264 WP_227173068.1 Txe/YoeB family addiction module toxin -
J2887_RS21000 (J2887_20940) 4598175..4598339 - 165 Protein_4113 transposase -
J2887_RS21005 (J2887_20945) 4598437..4598661 + 225 WP_227173069.1 hypothetical protein -
J2887_RS21010 (J2887_20950) 4598822..4599094 + 273 WP_227173070.1 ribbon-helix-helix protein, CopG family -
J2887_RS21015 (J2887_20955) 4599091..4599372 + 282 WP_227173071.1 type II toxin-antitoxin system RelE/ParE family toxin -
J2887_RS21020 (J2887_20960) 4599502..4599954 + 453 WP_227173072.1 hypothetical protein -
J2887_RS21025 (J2887_20965) 4600077..4600463 + 387 WP_227173073.1 hypothetical protein -
J2887_RS21030 (J2887_20970) 4600655..4600882 + 228 WP_227173074.1 hypothetical protein -
J2887_RS21035 (J2887_20975) 4600930..4601634 + 705 WP_227173075.1 alpha/beta hydrolase -
J2887_RS21040 (J2887_20980) 4601704..4601964 + 261 WP_227173076.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11727.41 Da        Isoelectric Point: 4.4410

>T196927 WP_227173067.1 NZ_CP071785:4596927-4597229 [Marinobacter sp. CA1]
MAEVIWTEPALQELDAIAEYIALDNPAAARDLVQQVFDKTERLENFPQSGRIPPELPNSVYREVVVQPCRIFYREDERRV
LILYVMREERQLRAYMLGSS

Download         Length: 303 bp

>T196927 NZ_CP095514:c2163075-2162968 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCGTGATTTTCTGGCACGACCTGGCAGCACCGATCCTTGCGGGAATTATTACCGCAGCGAT
TGTTGGCTGGTGGCGTAGCCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9931.53 Da        Isoelectric Point: 8.5042

>AT196927 WP_227173066.1 NZ_CP071785:4596682-4596939 [Marinobacter sp. CA1]
MKVELVTNLKRQATKILADLHLTKEPVLITEHGQPSAYLVDVQDYEFMQRRLELLEGLSRGERAVLEGRMYSQSEAREKM
SKWLK

Download         Length: 258 bp

>AT196927 NZ_CP095514:2163131-2163192 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTGACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References