Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-brnA/ParE-BrnA
Location 3289758..3290417 Replicon chromosome
Accession NZ_CP071785
Organism Marinobacter sp. CA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J2887_RS15000 Protein ID WP_227171906.1
Coordinates 3289758..3290015 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag J2887_RS15005 Protein ID WP_227171907.1
Coordinates 3290112..3290417 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J2887_RS14965 (J2887_14925) 3284962..3286122 - 1161 WP_227171899.1 recombination-associated protein RdgC -
J2887_RS14970 (J2887_14930) 3286136..3286570 - 435 WP_227171900.1 hypothetical protein -
J2887_RS14980 (J2887_14940) 3287108..3287656 + 549 WP_227171902.1 helix-turn-helix transcriptional regulator -
J2887_RS14985 (J2887_14945) 3287607..3288476 + 870 WP_227171903.1 hypothetical protein -
J2887_RS14990 (J2887_14950) 3288655..3289383 + 729 WP_227171904.1 hypothetical protein -
J2887_RS14995 (J2887_14955) 3289384..3289761 - 378 WP_227171905.1 helix-turn-helix transcriptional regulator -
J2887_RS15000 (J2887_14960) 3289758..3290015 - 258 WP_227171906.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J2887_RS15005 (J2887_14965) 3290112..3290417 - 306 WP_227171907.1 BrnA antitoxin family protein Antitoxin
J2887_RS15010 (J2887_14970) 3290401..3290685 - 285 WP_227171908.1 BrnT family toxin -
J2887_RS15015 (J2887_14975) 3290838..3291227 + 390 WP_227171909.1 helix-turn-helix transcriptional regulator -
J2887_RS15020 (J2887_14980) 3291257..3291559 + 303 WP_227171910.1 hypothetical protein -
J2887_RS15025 (J2887_14985) 3291556..3291861 + 306 WP_227171911.1 hypothetical protein -
J2887_RS15030 (J2887_14990) 3291855..3292037 + 183 WP_227171912.1 carbon storage regulator -
J2887_RS15035 (J2887_14995) 3292421..3292759 + 339 WP_227171913.1 hypothetical protein -
J2887_RS15040 (J2887_15000) 3292756..3293073 + 318 WP_227171914.1 hypothetical protein -
J2887_RS15045 (J2887_15005) 3293070..3294791 + 1722 WP_227171915.1 DNA cytosine methyltransferase -
J2887_RS15050 (J2887_15010) 3294788..3295144 + 357 WP_227171916.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3256211..3301761 45550


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(31-89)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9721.48 Da        Isoelectric Point: 10.2590

>T196926 WP_227171906.1 NZ_CP071785:c3290015-3289758 [Marinobacter sp. CA1]
MHKLTYKKSALKALRKMPRPQAQKLQCELSVIAKDPYAYSGDWKPLKGEPYWRLRQGGYRAVCSIDDGELLVLVLKVGPR
GDVYK

Download         Length: 258 bp

>T196926 NZ_CP095514:c1420239-1420021 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11517.93 Da        Isoelectric Point: 4.9752

>AT196926 WP_227171907.1 NZ_CP071785:c3290417-3290112 [Marinobacter sp. CA1]
MQIKTKSGRVIQLPTDEEDAEINAGIAADPDTYELSDEDFKRLRPMGRPKAEVTKERITIRLSPDVVEAFRATGKGWQSR
MDKALREYVQEHSQSDIERLG

Download         Length: 306 bp

>AT196926 NZ_CP095514:c1420639-1420265 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References