Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE(toxin) |
| Location | 3289384..3290015 | Replicon | chromosome |
| Accession | NZ_CP071785 | ||
| Organism | Marinobacter sp. CA1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | J2887_RS15000 | Protein ID | WP_227171906.1 |
| Coordinates | 3289758..3290015 (-) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | J2887_RS14995 | Protein ID | WP_227171905.1 |
| Coordinates | 3289384..3289761 (-) | Length | 126 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J2887_RS14965 (J2887_14925) | 3284962..3286122 | - | 1161 | WP_227171899.1 | recombination-associated protein RdgC | - |
| J2887_RS14970 (J2887_14930) | 3286136..3286570 | - | 435 | WP_227171900.1 | hypothetical protein | - |
| J2887_RS14980 (J2887_14940) | 3287108..3287656 | + | 549 | WP_227171902.1 | helix-turn-helix transcriptional regulator | - |
| J2887_RS14985 (J2887_14945) | 3287607..3288476 | + | 870 | WP_227171903.1 | hypothetical protein | - |
| J2887_RS14990 (J2887_14950) | 3288655..3289383 | + | 729 | WP_227171904.1 | hypothetical protein | - |
| J2887_RS14995 (J2887_14955) | 3289384..3289761 | - | 378 | WP_227171905.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| J2887_RS15000 (J2887_14960) | 3289758..3290015 | - | 258 | WP_227171906.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| J2887_RS15005 (J2887_14965) | 3290112..3290417 | - | 306 | WP_227171907.1 | BrnA antitoxin family protein | - |
| J2887_RS15010 (J2887_14970) | 3290401..3290685 | - | 285 | WP_227171908.1 | BrnT family toxin | - |
| J2887_RS15015 (J2887_14975) | 3290838..3291227 | + | 390 | WP_227171909.1 | helix-turn-helix transcriptional regulator | - |
| J2887_RS15020 (J2887_14980) | 3291257..3291559 | + | 303 | WP_227171910.1 | hypothetical protein | - |
| J2887_RS15025 (J2887_14985) | 3291556..3291861 | + | 306 | WP_227171911.1 | hypothetical protein | - |
| J2887_RS15030 (J2887_14990) | 3291855..3292037 | + | 183 | WP_227171912.1 | carbon storage regulator | - |
| J2887_RS15035 (J2887_14995) | 3292421..3292759 | + | 339 | WP_227171913.1 | hypothetical protein | - |
| J2887_RS15040 (J2887_15000) | 3292756..3293073 | + | 318 | WP_227171914.1 | hypothetical protein | - |
| J2887_RS15045 (J2887_15005) | 3293070..3294791 | + | 1722 | WP_227171915.1 | DNA cytosine methyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 3256211..3301761 | 45550 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9721.48 Da Isoelectric Point: 10.2590
>T196925 WP_227171906.1 NZ_CP071785:c3290015-3289758 [Marinobacter sp. CA1]
MHKLTYKKSALKALRKMPRPQAQKLQCELSVIAKDPYAYSGDWKPLKGEPYWRLRQGGYRAVCSIDDGELLVLVLKVGPR
GDVYK
MHKLTYKKSALKALRKMPRPQAQKLQCELSVIAKDPYAYSGDWKPLKGEPYWRLRQGGYRAVCSIDDGELLVLVLKVGPR
GDVYK
Download Length: 258 bp
>T196925 NZ_CP095514:c1121619-1121242 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCAACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCAGGATTC
AGCGCTTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGACCCGCAG
CAACTACAGAATGGTGAACGACATCATCCGGGGTGAACATTCGGAGGCGAAACGATGA
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCAACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCAGGATTC
AGCGCTTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGACCCGCAG
CAACTACAGAATGGTGAACGACATCATCCGGGGTGAACATTCGGAGGCGAAACGATGA
Antitoxin
Download Length: 126 a.a. Molecular weight: 13428.18 Da Isoelectric Point: 4.2393
>AT196925 WP_227171905.1 NZ_CP071785:c3289761-3289384 [Marinobacter sp. CA1]
MSAQIIEREGKPEYAVLPYSEYLELLALAEEVKDAADARQAMSELKNGEDEVVPAVVADRLIAGDEHPLKVWREYRGLTQ
EALGAAAGVGKSYISQIEGAGKTASTKVLKALAQALSVDVDDLIE
MSAQIIEREGKPEYAVLPYSEYLELLALAEEVKDAADARQAMSELKNGEDEVVPAVVADRLIAGDEHPLKVWREYRGLTQ
EALGAAAGVGKSYISQIEGAGKTASTKVLKALAQALSVDVDDLIE
Download Length: 378 bp
>AT196925 NZ_CP095514:c1122040-1121666 [Escherichia coli]
GTGTCAGACACGCTCCATGAAACAAATTATCCCGACGACAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGGCAGT
TCAGCGACGCGGATGCATACCATCTGGACCAGGCTTTTCCACTGCTGATGAAACAACTGGAACTCATGCTCACCATCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAGAGGGCTGACCTGCGAAGCCGACACCCTCGGCAGCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA
GTGTCAGACACGCTCCATGAAACAAATTATCCCGACGACAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGGCAGT
TCAGCGACGCGGATGCATACCATCTGGACCAGGCTTTTCCACTGCTGATGAAACAACTGGAACTCATGCTCACCATCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAGAGGGCTGACCTGCGAAGCCGACACCCTCGGCAGCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|