Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 3289384..3290015 Replicon chromosome
Accession NZ_CP071785
Organism Marinobacter sp. CA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J2887_RS15000 Protein ID WP_227171906.1
Coordinates 3289758..3290015 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J2887_RS14995 Protein ID WP_227171905.1
Coordinates 3289384..3289761 (-) Length 126 a.a.

Genomic Context

J2887_RS14980J2887_RS14985J2887_RS14990J2887_RS15015J2887_RS15020J2887_RS15025J2887_RS15030J2887_RS15035J2887_RS15040J2887_RS15045J2887_RS14965J2887_RS14970J2887_RS14995J2887_RS15000J2887_RS15005J2887_RS15010
Location: 3287108..3287656 (549 bp)
Type: Others
Protein ID: WP_227171902.1
Location: 3287607..3288476 (870 bp)
Type: Others
Protein ID: WP_227171903.1
Location: 3288655..3289383 (729 bp)
Type: Others
Protein ID: WP_227171904.1
Location: 3290838..3291227 (390 bp)
Type: Others
Protein ID: WP_227171909.1
Location: 3291257..3291559 (303 bp)
Type: Others
Protein ID: WP_227171910.1
Location: 3291556..3291861 (306 bp)
Type: Others
Protein ID: WP_227171911.1
Location: 3291855..3292037 (183 bp)
Type: Others
Protein ID: WP_227171912.1
Location: 3292421..3292759 (339 bp)
Type: Others
Protein ID: WP_227171913.1
Location: 3292756..3293073 (318 bp)
Type: Others
Protein ID: WP_227171914.1
Location: 3293070..3294791 (1722 bp)
Type: Others
Protein ID: WP_227171915.1
Location: 3284962..3286122 (1161 bp)
Type: Others
Protein ID: WP_227171899.1
Location: 3286136..3286570 (435 bp)
Type: Others
Protein ID: WP_227171900.1
Location: 3289384..3289761 (378 bp)
Type: Antitoxin
Protein ID: WP_227171905.1
Location: 3289758..3290015 (258 bp)
Type: Toxin
Protein ID: WP_227171906.1
Location: 3290112..3290417 (306 bp)
Type: Others
Protein ID: WP_227171907.1
Location: 3290401..3290685 (285 bp)
Type: Others
Protein ID: WP_227171908.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J2887_RS14965 (J2887_14925)3284962..3286122-1161WP_227171899.1recombination-associated protein RdgC-
J2887_RS14970 (J2887_14930)3286136..3286570-435WP_227171900.1hypothetical protein-
J2887_RS14980 (J2887_14940)3287108..3287656+549WP_227171902.1helix-turn-helix transcriptional regulator-
J2887_RS14985 (J2887_14945)3287607..3288476+870WP_227171903.1hypothetical protein-
J2887_RS14990 (J2887_14950)3288655..3289383+729WP_227171904.1hypothetical protein-
J2887_RS14995 (J2887_14955)3289384..3289761-378WP_227171905.1helix-turn-helix transcriptional regulatorAntitoxin
J2887_RS15000 (J2887_14960)3289758..3290015-258WP_227171906.1type II toxin-antitoxin system RelE/ParE family toxinToxin
J2887_RS15005 (J2887_14965)3290112..3290417-306WP_227171907.1BrnA antitoxin family protein-
J2887_RS15010 (J2887_14970)3290401..3290685-285WP_227171908.1BrnT family toxin-
J2887_RS15015 (J2887_14975)3290838..3291227+390WP_227171909.1helix-turn-helix transcriptional regulator-
J2887_RS15020 (J2887_14980)3291257..3291559+303WP_227171910.1hypothetical protein-
J2887_RS15025 (J2887_14985)3291556..3291861+306WP_227171911.1hypothetical protein-
J2887_RS15030 (J2887_14990)3291855..3292037+183WP_227171912.1carbon storage regulator-
J2887_RS15035 (J2887_14995)3292421..3292759+339WP_227171913.1hypothetical protein-
J2887_RS15040 (J2887_15000)3292756..3293073+318WP_227171914.1hypothetical protein-
J2887_RS15045 (J2887_15005)3293070..3294791+1722WP_227171915.1DNA cytosine methyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--3256211..330176145550


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(69-123)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9721.48 Da        Isoelectric Point: 10.2590

>T196925 WP_227171906.1 NZ_CP071785:c3290015-3289758 [Marinobacter sp. CA1]
MHKLTYKKSALKALRKMPRPQAQKLQCELSVIAKDPYAYSGDWKPLKGEPYWRLRQGGYRAVCSIDDGELLVLVLKVGPR
GDVYK

Download         Length: 258 bp

>T196925 NZ_CP095514:c1121619-1121242 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCAACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCAGGATTC
AGCGCTTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGACCCGCAG
CAACTACAGAATGGTGAACGACATCATCCGGGGTGAACATTCGGAGGCGAAACGATGA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 13428.18 Da        Isoelectric Point: 4.2393

>AT196925 WP_227171905.1 NZ_CP071785:c3289761-3289384 [Marinobacter sp. CA1]
MSAQIIEREGKPEYAVLPYSEYLELLALAEEVKDAADARQAMSELKNGEDEVVPAVVADRLIAGDEHPLKVWREYRGLTQ
EALGAAAGVGKSYISQIEGAGKTASTKVLKALAQALSVDVDDLIE

Download         Length: 378 bp

>AT196925 NZ_CP095514:c1122040-1121666 [Escherichia coli]
GTGTCAGACACGCTCCATGAAACAAATTATCCCGACGACAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGGCAGT
TCAGCGACGCGGATGCATACCATCTGGACCAGGCTTTTCCACTGCTGATGAAACAACTGGAACTCATGCTCACCATCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAGAGGGCTGACCTGCGAAGCCGACACCCTCGGCAGCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References