Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yoeB-relB/YoeB-YefM |
| Location | 334633..335135 | Replicon | chromosome |
| Accession | NZ_CP071785 | ||
| Organism | Marinobacter sp. CA1 | ||
Toxin (Protein)
| Gene name | yoeB | Uniprot ID | - |
| Locus tag | J2887_RS01505 | Protein ID | WP_227173658.1 |
| Coordinates | 334633..334887 (-) | Length | 85 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | J2887_RS01510 | Protein ID | WP_227173659.1 |
| Coordinates | 334884..335135 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J2887_RS21650 (J2887_01450) | 329647..329925 | + | 279 | Protein_287 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| J2887_RS01465 (J2887_01455) | 329936..330250 | + | 315 | WP_227173647.1 | HigA family addiction module antitoxin | - |
| J2887_RS01470 (J2887_01460) | 330534..330719 | + | 186 | WP_267461609.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| J2887_RS01475 (J2887_01465) | 330719..331012 | + | 294 | WP_227173649.1 | HigA family addiction module antitoxin | - |
| J2887_RS01480 (J2887_01470) | 331354..332493 | - | 1140 | WP_227173627.1 | IS110 family transposase | - |
| J2887_RS01485 (J2887_01475) | 332625..333203 | + | 579 | WP_227173650.1 | plasmid pRiA4b ORF-3 family protein | - |
| J2887_RS01490 (J2887_01480) | 333434..333751 | - | 318 | WP_227173652.1 | CcdB family protein | - |
| J2887_RS01495 (J2887_01485) | 333751..333996 | - | 246 | WP_227173654.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
| J2887_RS01500 (J2887_01490) | 334130..334531 | - | 402 | WP_227173656.1 | PIN domain nuclease | - |
| J2887_RS01505 (J2887_01495) | 334633..334887 | - | 255 | WP_227173658.1 | Txe/YoeB family addiction module toxin | Toxin |
| J2887_RS01510 (J2887_01500) | 334884..335135 | - | 252 | WP_227173659.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| J2887_RS01515 (J2887_01505) | 335328..335693 | - | 366 | WP_227173661.1 | histidine triad nucleotide-binding protein | - |
| J2887_RS01520 (J2887_01510) | 335740..337035 | - | 1296 | WP_227173663.1 | FAD-dependent monooxygenase | - |
| J2887_RS01525 (J2887_01515) | 337149..337709 | - | 561 | WP_227173665.1 | YbaK/EbsC family protein | - |
| J2887_RS01530 (J2887_01520) | 337922..338755 | - | 834 | WP_227173667.1 | mechanosensitive ion channel | - |
| J2887_RS01535 (J2887_01525) | 338900..339991 | - | 1092 | WP_227173669.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | flgI / lfgG / flgC / lfiI / lfhA / fliP | 262529..643278 | 380749 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10199.76 Da Isoelectric Point: 9.8161
>T196924 WP_227173658.1 NZ_CP071785:c334887-334633 [Marinobacter sp. CA1]
MKLVFSENAWEDYLYWQKTDKKILNRINKLIKETKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALLIAQL
RYNY
MKLVFSENAWEDYLYWQKTDKKILNRINKLIKETKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALLIAQL
RYNY
Download Length: 255 bp
>T196924 NZ_CP095514:922580-922894 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9287.53 Da Isoelectric Point: 4.6258
>AT196924 WP_227173659.1 NZ_CP071785:c335135-334884 [Marinobacter sp. CA1]
MDAISYTAARTNLAKTMEQVCEDHSPVVITRSKSQSVVMMSLEDYEALQETAYLLRAPKNARRLLESVAELEQGGGREKD
LLE
MDAISYTAARTNLAKTMEQVCEDHSPVVITRSKSQSVVMMSLEDYEALQETAYLLRAPKNARRLLESVAELEQGGGREKD
LLE
Download Length: 252 bp
>AT196924 NZ_CP095514:922344-922577 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|