Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-MazE
Location 82596..83191 Replicon chromosome
Accession NZ_CP071753
Organism Burkholderia pseudomallei strain VBM23831

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag J3C54_RS30790 Protein ID WP_207876710.1
Coordinates 82841..83191 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag J3C54_RS30785 Protein ID WP_017425280.1
Coordinates 82596..82847 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3C54_RS30750 (J3C54_30750) 78129..79040 - 912 WP_207876705.1 SOS response-associated peptidase family protein -
J3C54_RS30755 (J3C54_30755) 79167..79493 - 327 WP_207876736.1 H-NS histone family protein -
J3C54_RS30760 (J3C54_30760) 79781..80116 + 336 WP_207876706.1 hypothetical protein -
J3C54_RS30770 (J3C54_30770) 80690..81076 - 387 WP_243435628.1 hypothetical protein -
J3C54_RS30775 (J3C54_30775) 81266..81592 - 327 WP_207876708.1 H-NS histone family protein -
J3C54_RS30780 (J3C54_30780) 81756..82427 + 672 WP_207876709.1 site-specific integrase -
J3C54_RS30785 (J3C54_30785) 82596..82847 + 252 WP_017425280.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
J3C54_RS30790 (J3C54_30790) 82841..83191 + 351 WP_207876710.1 type II toxin-antitoxin system ChpB family toxin Toxin
J3C54_RS30795 (J3C54_30795) 83209..83394 + 186 WP_060349285.1 hypothetical protein -
J3C54_RS30800 (J3C54_30800) 83408..83647 + 240 WP_207876711.1 hypothetical protein -
J3C54_RS30805 (J3C54_30805) 84144..84581 + 438 WP_207876712.1 hypothetical protein -
J3C54_RS30810 (J3C54_30810) 84578..85024 + 447 WP_243435629.1 hypothetical protein -
J3C54_RS30815 (J3C54_30815) 85045..85287 + 243 WP_207876713.1 hypothetical protein -
J3C54_RS30820 (J3C54_30820) 85322..85954 + 633 WP_207876714.1 DUF262 domain-containing protein -
J3C54_RS30825 (J3C54_30825) 85971..86195 + 225 WP_081053968.1 hypothetical protein -
J3C54_RS30830 (J3C54_30830) 86206..86394 + 189 WP_243435630.1 hypothetical protein -
J3C54_RS30835 (J3C54_30835) 86426..86680 + 255 WP_194794506.1 hypothetical protein -
J3C54_RS30840 (J3C54_30840) 86715..87029 + 315 WP_207876715.1 hypothetical protein -
J3C54_RS30845 (J3C54_30845) 87053..87697 + 645 WP_207876716.1 hypothetical protein -
J3C54_RS30850 (J3C54_30850) 87838..88083 + 246 WP_207876717.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-116)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12391.35 Da        Isoelectric Point: 9.9894

>T196852 WP_207876710.1 NZ_CP071753:82841-83191 [Burkholderia pseudomallei]
MVKRVKFERGDIVRVSLNPTMGKEQQGNFRPALVLSPAAFNALGVALVAPITQGGEFARYAGFAVPLSGSGTETQGVALV
NMVRTLDLDARGARKVERAPVEVVEDALARLQTILE

Download         Length: 351 bp

>T196852 NZ_CP095463:197786-198115 [Streptococcus suis]
ATGGAATTTGAGTCTTATTCAGTGATACTTGCTCCAGCAGTGGAGAAGGAATTGGCAGTTATTTACGCCTATTTTTCGGA
ACAGTTCTCAGAAGAAATTGCCAAAAGACGAATTGGGATGATTGTCGAAGCATTAGAGAGTTTGCAAATTTTTCCTGAAC
GTGGTTTTAACGCCGATAACCGTTTTGGTAAGCAGATAGACCCGCCTCATCTAACCCGAGGCTATGTCGTTGGAAAAGAC
TACATCGCCCTCTATCGCGTAGTGAAAAATGAAGTTCGAGTTGGTCATCTTTTTGCGACCAAGAGTGATTATGTGAAGTT
GTTGAAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8812.98 Da        Isoelectric Point: 4.4645

>AT196852 WP_017425280.1 NZ_CP071753:82596-82847 [Burkholderia pseudomallei]
MELKIQKWGNSAAVRLPAVLLEQIGASAGSSLNADVRPDGVLLTPARRKYSLDELVAQCDANAPEPADLAAWGEVNAVGR
EAW

Download         Length: 252 bp

>AT196852 NZ_CP095463:197509-197796 [Streptococcus suis]
TTGATAACTATAAATAAAGATGCCCAAGTAAATTTTAAAACTGATTCCAGACTTTTAGAAAAAGCCAAGGAAGTATTTGC
TATGAACCAGCTGGATTTGACTGCTGGTTTTAACCTCTTCTTGCAAAATATCGCTGTAAAAAATGAGTTGCCAATTCTGA
CAGAAGAAGAGTTGGAAAGAGAAGAGTTGTTTTTACAGTTACAGAAGGAAATCCAGGAAAACCAACAGGCGATTGAGGCA
GGTCACGGGATCAGCCTAGAAAGTGTCAAAGAGAAGTATGGAATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References