Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1955945..1956089 Replicon chromosome
Accession NZ_CP071734
Organism Klebsiella variicola strain KGB_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1955981..1956083 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1955945..1956089 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGB1_RS09555 (KGB1_09550) 1951075..1953135 + 2061 WP_012541258.1 oligopeptidase B -
KGB1_RS09560 (KGB1_09555) 1953139..1953798 - 660 WP_008804267.1 exodeoxyribonuclease X -
KGB1_RS09565 (KGB1_09560) 1953877..1954107 - 231 WP_012541260.1 DNA polymerase III subunit theta -
KGB1_RS09570 (KGB1_09565) 1954221..1954595 + 375 WP_012541261.1 CopC domain-containing protein YobA -
KGB1_RS09575 (KGB1_09570) 1954599..1955468 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
KGB1_RS09580 (KGB1_09575) 1955485..1955823 + 339 WP_008804271.1 YebY family protein -
- 1955945..1956089 - 145 - - Antitoxin
- 1955981..1956083 + 103 - - Toxin
KGB1_RS09585 (KGB1_09580) 1956468..1956611 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
KGB1_RS09590 (KGB1_09585) 1956715..1957683 - 969 WP_163595291.1 VirK/YbjX family protein -
KGB1_RS09595 (KGB1_09590) 1957840..1958493 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
KGB1_RS09600 (KGB1_09595) 1958490..1958681 - 192 WP_002911395.1 YebW family protein -
KGB1_RS09605 (KGB1_09600) 1958779..1959018 - 240 WP_002911393.1 YebV family protein -
KGB1_RS09610 (KGB1_09605) 1959134..1960567 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T196821 NZ_CP071734:1955981-1956083 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT196821 NZ_CP071734:c1956089-1955945 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References