196751

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2802961..2803508 Replicon chromosome
Accession NZ_CP071708
Organism Vibrio sp. ABG19

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J0X00_RS18975 Protein ID WP_282477484.1
Coordinates 2803206..2803508 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J0X00_RS18970 Protein ID WP_136486645.1
Coordinates 2802961..2803218 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0X00_RS18950 (J0X00_18930) 2798552..2799196 + 645 WP_282477482.1 hypothetical protein -
J0X00_RS18955 (J0X00_18935) 2799241..2800195 - 955 Protein_2411 IS110 family transposase -
J0X00_RS18960 (J0X00_18940) 2800547..2801110 + 564 WP_282477483.1 pyridoxamine 5'-phosphate oxidase family protein -
J0X00_RS18965 (J0X00_18945) 2801253..2802455 + 1203 WP_282476458.1 IS256 family transposase -
J0X00_RS18970 (J0X00_18950) 2802961..2803218 + 258 WP_136486645.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J0X00_RS18975 (J0X00_18955) 2803206..2803508 + 303 WP_282477484.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J0X00_RS18980 (J0X00_18960) 2803501..2803919 - 419 Protein_2416 IS66 family transposase -
J0X00_RS18985 (J0X00_18965) 2803979..2804221 - 243 WP_282477485.1 IS66 family insertion sequence element accessory protein TnpB -
J0X00_RS18990 2804271..2804423 - 153 Protein_2418 IS66 family insertion sequence element accessory protein TnpB -
J0X00_RS18995 (J0X00_18970) 2804938..2805777 + 840 WP_282477486.1 5-dehydro-4-deoxy-D-glucuronate isomerase -
J0X00_RS19000 (J0X00_18975) 2805837..2806826 + 990 WP_282477487.1 TRAP transporter substrate-binding protein -
J0X00_RS19005 (J0X00_18980) 2806883..2807410 + 528 WP_282477488.1 TRAP transporter small permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11701.74 Da        Isoelectric Point: 5.8918

>T196751 WP_282477484.1 NZ_CP071708:2803206-2803508 [Vibrio sp. ABG19]
MAKIIWTEPALSDLDDIAEYIALEKFVAAKQLVQTIFAKVERLETFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRVERDLRKFLLSKV

Download         Length: 303 bp

>T196751 NZ_CP095376:c9288098-9287838 [Amycolatopsis pretoriensis]
ATGAAGCTGGTTTGGGACGAGCTCGCTTGGCATGACTACCTCTGGTGGCAGACCGAAGACCGGAAGGTTCTCAAGCGCAT
CAACGCACTGCTCGAGGATGTCCGGCGGAACGGCAACGAGGGTCTCGGCAAACCTGAACCCCTGAAGCACGGCTTCCAGG
GTTACTGGTCACGCCGGATCACAGACGAGCACCGGCTCGTCTACAAGATCGCCGAAGACGAGATTCGCATCGCGGCCTGT
CGCTACCACTACGGGAAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9698.21 Da        Isoelectric Point: 6.7273

>AT196751 WP_136486645.1 NZ_CP071708:2802961-2803218 [Vibrio sp. ABG19]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLSILEGIARGERALTDGKMVSHEEAKDKM
SKWLK

Download         Length: 258 bp

>AT196751 NZ_CP095376:c9288337-9288095 [Amycolatopsis pretoriensis]
ATGAGCTACTCCGAGTCTCGCGCGAAGTACGCCGAGACGCTCGACTCCGTGGTCAACGACCGCGAAGAGGTCGTGATCAC
TCGCGCCGGGCACGAACCGGTCGTGATTGTTTCCCTTGACGACTACCAGTCGCTCAAGGAAACCGCCTATCTGCTTCGCA
GCCCTGAGAACGCGCGACGTTTGATCACGGCAATCGAGCGGCTGGAGTCCGGCGGCGGGACACAGCACGAACTTGTGGAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References