Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5429526..5430045 Replicon chromosome
Accession NZ_CP071706
Organism Pseudomonas donghuensis strain P482

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BV82_RS25275 Protein ID WP_036994993.1
Coordinates 5429526..5429816 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BV82_RS25280 Protein ID WP_036994992.1
Coordinates 5429806..5430045 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BV82_RS25255 (BV82_1754) 5424597..5425892 + 1296 WP_081839646.1 antiviral reverse transcriptase Drt3a -
BV82_RS25260 (BV82_1753) 5425885..5427801 + 1917 WP_036994996.1 antiviral reverse transcriptase Drt3b -
BV82_RS25265 (BV82_1752) 5428350..5428688 + 339 WP_036995077.1 hypothetical protein -
BV82_RS25270 (BV82_1751) 5428763..5429095 - 333 WP_036994994.1 DUF3077 domain-containing protein -
BV82_RS25275 (BV82_1750) 5429526..5429816 - 291 WP_036994993.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BV82_RS25280 (BV82_1749) 5429806..5430045 - 240 WP_036994992.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BV82_RS25285 (BV82_25285) 5430507..5431385 + 879 Protein_4985 NAD(P)/FAD-dependent oxidoreductase -
BV82_RS25290 (BV82_1747) 5431486..5432478 - 993 WP_036994990.1 ADP-glyceromanno-heptose 6-epimerase -
BV82_RS25295 (BV82_1746) 5432613..5433059 - 447 WP_036994989.1 hypothetical protein -
BV82_RS25300 (BV82_1745) 5433056..5433961 - 906 WP_010221291.1 hypothetical protein -
BV82_RS25305 (BV82_1744) 5434039..5434998 - 960 WP_036994988.1 type VI secretion system-associated lipoprotein TagQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T196748 WP_036994993.1 NZ_CP071706:c5429816-5429526 [Pseudomonas donghuensis]
MTYSLEFDARALKEWHKLGDTIRAQFKKKLAAVLLEPRIEANRLRSLQDCYKIKLRSSGYRLVYQVIAQEVVVFVVAVDK
REREQVYRKASERLAD

Download         Length: 291 bp

>T196748 NZ_CP095282:c36332-35367 [Aeromonas hydrophila]
ATGCAGCCTAAAGATTCTTCGATTTTCGCCGACGTTTCTGACTACTTCGGGATCGATAACCCTGCGATAGCAGAAAAGGA
CTACTACGTCGTCCAGCTGCTCAAACTGCTTGCAAGTCATTCTTGCCAGCACCACACCATGGTGTTTGCAGGCGGGACCG
CATTAGCCAAAGCTGACGTCAAGCTTCAGCGCATGTCTGAAGATGTCGACATCAAGTTATCTGTTAACGATAGTGCTAAA
GATGAATCTCGAAGCGCGATGAAGCGCCATCGCAAAGCCATCAGAGATGGTTTGATTGAAGAGCTCAATGCGACTGGCGT
TTTCCAAGTAGAGAAGGCTGAGGTCACTTGTCGGGATGAGCACAGGTACATTGAAATGCCGGTGAGATACCCACAGGCCT
TCAGCAAGGCCCCCTGCCTTCGGCCTTTCATCAAGCTCGAACTCATTGAGACTGATCTGCTCGCAGGCCATAACCCCATG
CCCATTTGTTCGCTGCACAATGAAGCGATGCAGCAAGGACCTGAAGTGCCAGCCTTCAACACGGTTCCCCTGATCTCCAC
CCAAGCCGAGAAAGTGTTGTCGATGCTGCGCAGAACAGCCAGCGTCAAGCATGACCCAGAACGATTGGATGATGAGTCGT
TGGTTCGCCACATTTATGACACTTATCGCCTGCAACAAAGTACCACCTTTGATTTGGCCGAACTGGCAGGGCTGATAGCT
GAAGGGATGAAGATGGATCGTGATCGCTATGGTCCCCAACACCCCGAGTTTGCAGAAGATCCTATCGGTGTGATGCGGTT
TGGCCTGGATGTGATTGCTGGTGACTCCCTATACAAAGATCGTTATGAGGCGTTCGTGAAGCCGATGGTGTATGGGGATG
CGTTGACTTGGGATGAGGCATTTCGCGTGTTCGAGGCTGTTGCGCGCCAGGCTCTAGATCACATTGAGCAACACGAACTT
ATTTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8934.33 Da        Isoelectric Point: 4.8011

>AT196748 WP_036994992.1 NZ_CP071706:c5430045-5429806 [Pseudomonas donghuensis]
MASINVRIDDDLKARAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEDDEALLATVRERLAAPQRVKVALDDL

Download         Length: 240 bp

>AT196748 NZ_CP095282:c36720-36322 [Aeromonas hydrophila]
ATGACCATTGCAGACCGTGTTGAAGCACGAATCAAACGATCTAAGCGAGATGTGTTTCTCCGTGAGGATTTCGATGACTT
GGGCGGTTATGACCAAATAGGCAGAGCCTTACGCCAGATGTGTGAAAAGGGTCTGCTTCTGAAGGTCGGCTACGGCGTGT
ATGCAAAGGCACGGCGTAACCGGATCAATAGTCGCTTGATGATCGCCTCCCCTGGTGGTCCAGACGCCGTACTCATTGCT
ACGCTTGACCGCCTGAAAGTGCCTTACGAACTGAATGGCCTGACAGCAGCTTATGCCGCGGGGAAATCCACTCAGGTTCC
CGCCTTTATGGAAGTTAAGCCTAAAAAGCGTTTTTCCAGAAAGCTGAAAATTGGAAACAGAGTGTTCAATGCAGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References