Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 505344..505876 Replicon plasmid p3
Accession NZ_CP071681
Organism Rhizobium ruizarguesonis strain NZLR24

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J3P73_RS33420 Protein ID WP_130657753.1
Coordinates 505344..505637 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J3P73_RS33425 Protein ID WP_024320231.1
Coordinates 505634..505876 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3P73_RS33400 501065..502108 - 1044 WP_130774252.1 ABC transporter permease -
J3P73_RS33405 502108..503625 - 1518 WP_130707064.1 sugar ABC transporter ATP-binding protein -
J3P73_RS33410 503622..504620 - 999 WP_130657751.1 LacI family transcriptional regulator -
J3P73_RS33415 504819..505259 + 441 WP_130676544.1 fucose dissimilation pathway protein FucU -
J3P73_RS33420 505344..505637 - 294 WP_130657753.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J3P73_RS33425 505634..505876 - 243 WP_024320231.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
J3P73_RS33430 506042..506944 - 903 WP_163885091.1 MBL fold metallo-hydrolase -
J3P73_RS33435 507048..507680 - 633 WP_130680640.1 DsbA family protein -
J3P73_RS33440 507795..508679 + 885 WP_130666001.1 LysR family transcriptional regulator -
J3P73_RS33445 508840..509118 + 279 WP_018070756.1 acylphosphatase -
J3P73_RS33450 509261..509914 + 654 WP_130657757.1 Rieske (2Fe-2S) protein -
J3P73_RS33455 509911..510756 + 846 WP_018070754.1 aromatic ring-hydroxylating dioxygenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..681781 681781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11257.76 Da        Isoelectric Point: 4.9134

>T196646 WP_130657753.1 NZ_CP071681:c505637-505344 [Rhizobium ruizarguesonis]
MSFKLSAEAEDDIIAIAEQGIRMFGPGQAKRYHDELFALFDLIAVNPRIARERDEIDPPVRIHPFKAHLIVYRIEDDETI
FVIRTRHAHEDWASDSI

Download         Length: 294 bp

>T196646 NZ_CP095240:3436388-3437305 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8881.03 Da        Isoelectric Point: 9.7765

>AT196646 WP_024320231.1 NZ_CP071681:c505876-505634 [Rhizobium ruizarguesonis]
MATMNVSLPGPMKDWVEAQARTGRYSNASDYVRDLIRRDQTRNDKIAAMQSFVEAGLQSGVGIRSKDELFAEAMARANKS

Download         Length: 243 bp

>AT196646 NZ_CP095240:3435624-3436382 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGTCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References