Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 608963..609498 Replicon plasmid p1
Accession NZ_CP071679
Organism Rhizobium ruizarguesonis strain NZLR24

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3P73_RS27360 Protein ID WP_024319651.1
Coordinates 609223..609498 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I2GF38
Locus tag J3P73_RS27355 Protein ID WP_027688292.1
Coordinates 608963..609223 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3P73_RS27335 604758..605639 - 882 WP_003549874.1 ABC transporter permease -
J3P73_RS27340 605651..606469 - 819 WP_024319648.1 ABC transporter ATP-binding protein -
J3P73_RS27345 606564..607577 - 1014 WP_018072979.1 ABC transporter substrate-binding protein -
J3P73_RS27350 607931..608659 - 729 WP_024319649.1 FadR family transcriptional regulator -
J3P73_RS27355 608963..609223 + 261 WP_027688292.1 ribbon-helix-helix domain-containing protein Antitoxin
J3P73_RS27360 609223..609498 + 276 WP_024319651.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J3P73_RS27365 609505..610512 - 1008 WP_024319652.1 LacI family transcriptional regulator -
J3P73_RS27370 610720..612042 + 1323 WP_024319653.1 alpha-L-fucosidase -
J3P73_RS27375 612093..613316 + 1224 WP_018072986.1 sugar ABC transporter substrate-binding protein -
J3P73_RS27380 613399..614373 + 975 WP_024319654.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..760106 760106


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10754.45 Da        Isoelectric Point: 10.1520

>T196645 WP_024319651.1 NZ_CP071679:609223-609498 [Rhizobium ruizarguesonis]
MGIKWTSKAASDVARLYDFLTPVDRQAAVRTVRALTAAPARLLEQPRLGERLEEFDPREVRRILVGRCELRYEIQQSMIY
VLRLWHTREDR

Download         Length: 276 bp

>T196645 NZ_CP095240:3112871-3113254 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9756.97 Da        Isoelectric Point: 4.4964

>AT196645 WP_027688292.1 NZ_CP071679:608963-609223 [Rhizobium ruizarguesonis]
METKVLTAHVPLPLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDDGNLVEHQSVQAWADSLDSDE
PISLPR

Download         Length: 261 bp

>AT196645 NZ_CP095240:3112629-3112871 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References