Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 762354..762956 Replicon chromosome
Accession NZ_CP071678
Organism Rhizobium ruizarguesonis strain NZLR24

Toxin (Protein)


Gene name relE Uniprot ID J0V8Z1
Locus tag J3P73_RS03700 Protein ID WP_003545373.1
Coordinates 762354..762599 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C6B0G5
Locus tag J3P73_RS03705 Protein ID WP_003545376.1
Coordinates 762609..762956 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3P73_RS03660 757836..758267 + 432 WP_018486320.1 DUF2948 family protein -
J3P73_RS03665 758322..759620 + 1299 WP_130719622.1 histidinol dehydrogenase -
J3P73_RS03670 759625..760098 + 474 WP_018072486.1 UPF0262 family protein -
J3P73_RS03675 760095..760580 + 486 WP_018072487.1 low molecular weight phosphatase family protein -
J3P73_RS03680 760704..760922 + 219 WP_003545338.1 translation initiation factor IF-1 -
J3P73_RS03685 760980..761600 + 621 WP_003545339.1 Maf-like protein -
J3P73_RS03690 761736..761948 + 213 WP_018072488.1 DNA gyrase inhibitor YacG -
J3P73_RS03700 762354..762599 + 246 WP_003545373.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
J3P73_RS03705 762609..762956 + 348 WP_003545376.1 helix-turn-helix transcriptional regulator Antitoxin
J3P73_RS03710 763244..763522 - 279 WP_026238483.1 transposase -
J3P73_RS03715 763530..764975 - 1446 WP_130660885.1 HlyD family type I secretion periplasmic adaptor subunit -
J3P73_RS03720 764990..766705 - 1716 WP_027689564.1 type I secretion system permease/ATPase -
J3P73_RS03725 766796..767371 - 576 WP_018072494.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(60-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9034.61 Da        Isoelectric Point: 10.7504

>T196642 WP_003545373.1 NZ_CP071678:762354-762599 [Rhizobium ruizarguesonis]
MKRIAYSKAAAKALRKMQPKRAAAIVAKVEAFANGETVDLKKLQGSEFFRIRVGQDRVIIDDQTMQVLVIKAGPRGDIYN
E

Download         Length: 246 bp

>T196642 NZ_CP095240:2580456-2580824 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12534.06 Da        Isoelectric Point: 4.2544

>AT196642 WP_003545376.1 NZ_CP071678:762609-762956 [Rhizobium ruizarguesonis]
MGEIQKLTIDGKGYVLLSEDDYQDLVDVSDARAAKARIDAGEETWPEDVVKALIAGEDPVRVFRKHRGMSIKELAEKSGL
SQPYLSEIETGKKEGSLDALRSIASALDVDLDDVA

Download         Length: 348 bp

>AT196642 NZ_CP095240:2580238-2580459 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB J0V8Z1

Antitoxin

Source ID Structure
AlphaFold DB A0A3S3VVG8

References