Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 264722..266201 Replicon plasmid p3
Accession NZ_CP071635
Organism Rhizobium sp. NZLR1

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag J3O30_RS30295 Protein ID WP_131704615.1
Coordinates 264722..265591 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag J3O30_RS30300 Protein ID WP_131598842.1
Coordinates 265584..266201 (-) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3O30_RS30280 262164..262700 + 537 WP_207585655.1 conjugative transfer signal peptidase TraF -
J3O30_RS30285 262690..263853 + 1164 WP_207585656.1 conjugal transfer protein TraB -
J3O30_RS30290 263870..264487 + 618 WP_131704616.1 conjugal transfer protein TraH -
J3O30_RS30295 264722..265591 - 870 WP_131704615.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
J3O30_RS30300 265584..266201 - 618 WP_131598842.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
J3O30_RS30305 266817..267059 - 243 WP_130654290.1 helix-turn-helix domain-containing protein -
J3O30_RS30310 267262..267606 + 345 WP_164050716.1 transcriptional repressor TraM -
J3O30_RS30315 267610..268314 - 705 WP_131614001.1 autoinducer binding domain-containing protein -
J3O30_RS30320 268625..269923 - 1299 WP_207585657.1 IncP-type conjugal transfer protein TrbI -
J3O30_RS30325 269935..270375 - 441 WP_207585658.1 conjugal transfer protein TrbH -
J3O30_RS30330 270379..271191 - 813 WP_207585659.1 P-type conjugative transfer protein TrbG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..328074 328074


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-263)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(15-56)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32416.13 Da        Isoelectric Point: 5.0757

>T196640 WP_131704615.1 NZ_CP071635:c265591-264722 [Rhizobium sp. NZLR1]
MAKEIRNVGASVRARLLQLAKASGQSFDLVLTRFALERLLFRLSQSPHAGRFVLKGAMLMMSWFDNPHRGTRDLDLLGFG
DPSPDPMLETFREILAQEADDGVTFDADTLHVDRIREALDYGGLRLRVIASISGARINLTIDIGFGDALEPGVEVLDYPS
MLDFPMPRLRAYARETVIAEKFQAMVMLGRVNSRMKDFYDIWILSRSFDFGDDRLARAIAATFDRRETSIPIDLPDALTD
AFAKDQQKQRQWRAFVEGVAHNPGDLTDVIAEIATFLMPHAVAAARLDE

Download         Length: 870 bp

>T196640 NZ_CP095240:c1022142-1022040 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22280.80 Da        Isoelectric Point: 10.2141

>AT196640 WP_131598842.1 NZ_CP071635:c266201-265584 [Rhizobium sp. NZLR1]
MPGSVTQRQIARTVLTERGIARLVELRNAGVTAATMSRMERDGEVLRLARGLYQLPDAQLDVNHSLAEVAKRAPKGVICL
VSALAFHGLTDQLPGQIWLAIGRKDWAPKLDGPAMRIVRFTDGLLNESVEPHVIEGVPVRVFGIAKTIADCFRYRNKIGL
SVAIEGLQEALRQRRATPGEIANQAERGGVGSVIRPYLEALTANG

Download         Length: 618 bp

>AT196640 NZ_CP095240:1022033-1022178 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References