Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 171508..172310 Replicon plasmid p1
Accession NZ_CP071627
Organism Rhizobium leguminosarum strain GLR17

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag J3P71_RS26995 Protein ID WP_168302548.1
Coordinates 171508..172035 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag J3P71_RS27000 Protein ID WP_164577378.1
Coordinates 172032..172310 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3P71_RS26985 168094..169218 - 1125 WP_168267686.1 DNA repair exonuclease -
J3P71_RS26990 169567..171213 - 1647 WP_168302547.1 acetolactate synthase large subunit -
J3P71_RS26995 171508..172035 - 528 WP_168302548.1 GNAT family N-acetyltransferase Toxin
J3P71_RS27000 172032..172310 - 279 WP_164577378.1 DUF1778 domain-containing protein Antitoxin
J3P71_RS27005 172542..173337 - 796 Protein_169 exopolysaccharide synthesis protein -
J3P71_RS27010 173811..175925 - 2115 WP_168302549.1 carboxy terminal-processing peptidase -
J3P71_RS27015 176073..176552 - 480 WP_168302550.1 MEKHLA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..669795 669795


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(12-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18793.80 Da        Isoelectric Point: 9.8314

>T196630 WP_168302548.1 NZ_CP071627:c172035-171508 [Rhizobium leguminosarum]
VTLPVWHEEPIAKSHDRAAFDCGDAAMNEFIRRFARQSHEQNAAKTFCAIDKAQPHRILGFYTVAPSAVTHEAVPPKLTR
GLARHEVAGFKLARLATDIKVAGKGLGGQLIAAAALRCLRLASEGGGILLIIDAKSERAAHWYASYGAEPLQGKPLTLVM
PLATFAADFKAKGLL

Download         Length: 528 bp

>T196630 NZ_CP095234:3095232-3095717 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10162.85 Da        Isoelectric Point: 8.6184

>AT196630 WP_164577378.1 NZ_CP071627:c172310-172032 [Rhizobium leguminosarum]
MPRTADSKTERYQLRIPPKQKAMIARAAALSNKDMADFILDKIVPEAEAVIQAAEVETVSSRDFIRILDLLEHPPKPNAK
LRAAISALPDAL

Download         Length: 279 bp

>AT196630 NZ_CP095234:3094942-3095235 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References