Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 5185151..5185686 Replicon chromosome
Accession NZ_CP071626
Organism Rhizobium leguminosarum strain GLR17

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J3P71_RS25545 Protein ID WP_168303311.1
Coordinates 5185396..5185686 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J3P71_RS25540 Protein ID WP_026265506.1
Coordinates 5185151..5185399 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3P71_RS25525 5180738..5181760 - 1023 WP_168303314.1 galactose mutarotase -
J3P71_RS25530 5181988..5182911 - 924 WP_168303313.1 homoserine O-succinyltransferase -
J3P71_RS25535 5183152..5185044 + 1893 WP_205936868.1 ABC transporter ATP-binding protein/permease -
J3P71_RS25540 5185151..5185399 + 249 WP_026265506.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
J3P71_RS25545 5185396..5185686 + 291 WP_168303311.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J3P71_RS25550 5185724..5186353 - 630 WP_168303310.1 hypothetical protein -
J3P71_RS25555 5186474..5188291 - 1818 WP_168268663.1 ABC-F family ATP-binding cassette domain-containing protein -
J3P71_RS25560 5188295..5188951 - 657 WP_205936867.1 thiamine diphosphokinase -
J3P71_RS25565 5189009..5189536 - 528 WP_168303308.1 MarR family winged helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11368.87 Da        Isoelectric Point: 4.4325

>T196628 WP_168303311.1 NZ_CP071626:5185396-5185686 [Rhizobium leguminosarum]
MKYRTTIEADQDIVELYILGADQFGALQSEQYVDDLFDTFELLADNPRMARERRELNPPTRLHPYLAHMIAYTIREEDIL
IVRVLHGREDWQSLFA

Download         Length: 291 bp

>T196628 NZ_CP095234:2680437-2680805 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9348.56 Da        Isoelectric Point: 9.7724

>AT196628 WP_026265506.1 NZ_CP071626:5185151-5185399 [Rhizobium leguminosarum]
MATMNVSLPDPMKEWVDAQTKTGRYSNASDYVRDLIRRDQERAGKLAELQRLITDGLESGVSDRSKADILREARERLAAR
RV

Download         Length: 249 bp

>AT196628 NZ_CP095234:2680219-2680440 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References