Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-DUF971
Location 3711272..3711860 Replicon chromosome
Accession NZ_CP071626
Organism Rhizobium leguminosarum strain GLR17

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag J3P71_RS18625 Protein ID WP_168306721.1
Coordinates 3711555..3711860 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag J3P71_RS18620 Protein ID WP_168270652.1
Coordinates 3711272..3711562 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3P71_RS18600 3706929..3707843 - 915 WP_168306725.1 HD-GYP domain-containing protein -
J3P71_RS18605 3707974..3708210 - 237 WP_168306724.1 hypothetical protein -
J3P71_RS18610 3708324..3709427 + 1104 WP_168306723.1 branched-chain amino acid ABC transporter substrate-binding protein -
J3P71_RS18615 3709546..3711243 + 1698 WP_168306722.1 adenine deaminase -
J3P71_RS18620 3711272..3711562 - 291 WP_168270652.1 putative addiction module antidote protein Antitoxin
J3P71_RS18625 3711555..3711860 - 306 WP_168306721.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J3P71_RS18630 3711935..3713581 - 1647 WP_168306720.1 alpha-glucosidase family protein -
J3P71_RS18635 3713869..3715449 + 1581 WP_168306719.1 peptide ABC transporter substrate-binding protein -
J3P71_RS18640 3715498..3716421 + 924 WP_020051165.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(10-93)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11279.96 Da        Isoelectric Point: 10.1612

>T196626 WP_168306721.1 NZ_CP071626:c3711860-3711555 [Rhizobium leguminosarum]
MFILKQTATFRKWHKKLKDGKAKATIALRLQRLATGHAGDASPIGEGLSELRIHYGPGYRVYYCKRGETIIVLLCGGDKS
TQETDIRTAKRIASEWSDDNG

Download         Length: 306 bp

>T196626 NZ_CP095234:c1950139-1949222 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10360.86 Da        Isoelectric Point: 4.6486

>AT196626 WP_168270652.1 NZ_CP071626:c3711562-3711272 [Rhizobium leguminosarum]
MAEQIFDFDPAEMLDSDEAIEAFIIEALQTGDAKFIASALGVVARAKGMSKISRETGLAREHLYKALSENGNPTLETTLA
VMKAIGLELTTKHHAV

Download         Length: 291 bp

>AT196626 NZ_CP095234:c1950903-1950145 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGTCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References