Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 804999..805601 Replicon chromosome
Accession NZ_CP071626
Organism Rhizobium leguminosarum strain GLR17

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J3P71_RS04020 Protein ID WP_168306192.1
Coordinates 804999..805244 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J3P71_RS04025 Protein ID WP_168306185.1
Coordinates 805254..805601 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3P71_RS03990 800315..800530 + 216 WP_168306180.1 hypothetical protein -
J3P71_RS03995 800779..801021 - 243 WP_168306181.1 hypothetical protein -
J3P71_RS04000 801191..802114 - 924 WP_168306182.1 AAA family ATPase -
J3P71_RS04005 802495..802728 - 234 WP_168306183.1 hypothetical protein -
J3P71_RS04010 802731..802919 - 189 WP_168306191.1 helix-turn-helix domain-containing protein -
J3P71_RS04015 803534..804712 + 1179 WP_168306184.1 site-specific integrase -
J3P71_RS04020 804999..805244 + 246 WP_168306192.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
J3P71_RS04025 805254..805601 + 348 WP_168306185.1 helix-turn-helix transcriptional regulator Antitoxin
J3P71_RS04030 805763..806041 - 279 WP_003545380.1 transposase -
J3P71_RS04035 806049..807494 - 1446 WP_168306186.1 HlyD family type I secretion periplasmic adaptor subunit -
J3P71_RS04040 807509..809224 - 1716 WP_168269133.1 type I secretion system permease/ATPase -
J3P71_RS04045 809328..809903 - 576 WP_003545387.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 786175..822838 36663


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(63-113)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8956.47 Da        Isoelectric Point: 10.6486

>T196621 WP_168306192.1 NZ_CP071626:804999-805244 [Rhizobium leguminosarum]
MKKIAYSKAATKALRKMQPKRAAAIVAKVEAFANGETVDLKKLQGSDFFRIRVGQDRVIIDDQTLQVLVIKAGPRGDIDN
E

Download         Length: 246 bp

>T196621 NZ_CP095187:890208-890462 [Pseudoxanthomonas sp. F37]
GTGGACAACCGCGCGGCCGCCATCGAACGGGTCCGGCGCGTATTCGCGCATGTGGACCACCTGGCGGATCATCCCGACAG
CGGCCGCCGACCTCCTGAGCTGAAGCGCGGCCGCTATCGCCAGATCGTCGAACCGCCGTGCCGCGTGTTCCATCGATCAG
AGCCGGGGCGCGTGCTCATCCTGCATGTCATGCGCAGCGAGCGCCTGCTGCGGCCCGGCATGCTGCAAGCCCGCAAACCG
GGCAAGGCGCGCTGA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12548.09 Da        Isoelectric Point: 4.2622

>AT196621 WP_168306185.1 NZ_CP071626:805254-805601 [Rhizobium leguminosarum]
MGEIQKLTIDGKGYVLLSEEDYQDLVDVSDARAAKARIDAGEETWPEDVVKALIAGEDPVRVFRKHRGMSIKELAEKSGL
SQPYLSEIETGKKEGSLDALRSIASALDVDLDDVA

Download         Length: 348 bp

>AT196621 NZ_CP095187:889897-890154 [Pseudoxanthomonas sp. F37]
ATGCGCACCGAACTCGTCACCACGCTGAAGCGCCAGGCCACCGGGCTGCTGGCCGACGTCGAACGGGATCGCCAGCCGAT
CCTGATCACCCAGCACGGATTGCCCAGCGCGTATCGGGTCGACGTGGAAACCTGCGAAACGCTGCTGTCGCGCATGGCCG
TGCTGGAAGGCATCGCGCGCGGCGAGCAGGCCGTGGCCGAAGGTCGGGCGGTCGCCCATCCTCAAGCCAGGGACCGGCTT
GCCAGAGGGTTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References