Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 516291..516826 | Replicon | plasmid p1 |
Accession | NZ_CP071613 | ||
Organism | Rhizobium bangladeshense strain BLR175 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | J2J98_RS23365 | Protein ID | WP_207603528.1 |
Coordinates | 516551..516826 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | J2J98_RS23360 | Protein ID | WP_207603275.1 |
Coordinates | 516291..516551 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
J2J98_RS23340 | 511468..511794 | + | 327 | WP_064713213.1 | DUF2934 domain-containing protein | - |
J2J98_RS23345 | 511799..512218 | + | 420 | WP_138396564.1 | HD domain-containing protein | - |
J2J98_RS23350 | 512394..514790 | + | 2397 | WP_207603274.1 | PAS-domain containing protein | - |
J2J98_RS23355 | 515005..516201 | - | 1197 | Protein_479 | DUF2264 domain-containing protein | - |
J2J98_RS23360 | 516291..516551 | + | 261 | WP_207603275.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
J2J98_RS23365 | 516551..516826 | + | 276 | WP_207603528.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
J2J98_RS23370 | 516833..517840 | - | 1008 | WP_207603276.1 | substrate-binding domain-containing protein | - |
J2J98_RS23375 | 518049..519368 | + | 1320 | WP_207603277.1 | alpha-L-fucosidase | - |
J2J98_RS23380 | 519417..520640 | + | 1224 | WP_207603278.1 | extracellular solute-binding protein | - |
J2J98_RS23385 | 520709..521635 | + | 927 | WP_207603279.1 | ABC transporter permease subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | htpB | 1..644610 | 644610 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10929.58 Da Isoelectric Point: 10.2902
>T196611 WP_207603528.1 NZ_CP071613:516551-516826 [Rhizobium bangladeshense]
MEVKWTRKAVSDIARLYDFLSPVDRRAAARTVQALTAAPARLMEQPRLGERLEEFDPREVRRILVGRYELRYEIQQSTIY
VLRLWHTREDR
MEVKWTRKAVSDIARLYDFLSPVDRRAAARTVQALTAAPARLMEQPRLGERLEEFDPREVRRILVGRYELRYEIQQSTIY
VLRLWHTREDR
Download Length: 276 bp
>T196611 NZ_CP095180:c1132012-1131794 [Enterobacter roggenkampii]
ATGTCTGATAAACCACTCACAAAAATCGATTATTTGATGCGCTTACGACGTTGTCAGTCAATTGACACCCTCGAACGCGT
GATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCCGTATTTTATTCAGCCGCTGACCATCGTCTTGCTGAGC
TGACCATGAATAAGTTGTATGACAAAATCCCTACTTCTGTATGGAAATTTGTCCGTTAA
ATGTCTGATAAACCACTCACAAAAATCGATTATTTGATGCGCTTACGACGTTGTCAGTCAATTGACACCCTCGAACGCGT
GATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCCGTATTTTATTCAGCCGCTGACCATCGTCTTGCTGAGC
TGACCATGAATAAGTTGTATGACAAAATCCCTACTTCTGTATGGAAATTTGTCCGTTAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9743.05 Da Isoelectric Point: 4.6135
>AT196611 WP_207603275.1 NZ_CP071613:516291-516551 [Rhizobium bangladeshense]
METKVLTAHVPLPLAQKVDQLAMRLERSRGWIIKQALTAWIDQEEERRRLTLEALADVDGGNIVDHQSVQAWADSLDSDE
PISLPR
METKVLTAHVPLPLAQKVDQLAMRLERSRGWIIKQALTAWIDQEEERRRLTLEALADVDGGNIVDHQSVQAWADSLDSDE
PISLPR
Download Length: 261 bp
>AT196611 NZ_CP095180:c1132414-1132040 [Enterobacter roggenkampii]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAACCTTGATGAAAGCAACCATGGCTGGGTAAACGACCCAACGTCTGCCATCAATTTACAGTTGAATGAGCTGATAGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGCTCATTGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGTAGTTACGGCATTAACGCCCAGGATTTGCAAAAATGGCGTAAATCGGGAAACCGGCT
ATTCCGCTGTTTCGTCAACGTGAGCAGAGCTAACCCGGTTAGCCTTTCCTGTTAA
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAACCTTGATGAAAGCAACCATGGCTGGGTAAACGACCCAACGTCTGCCATCAATTTACAGTTGAATGAGCTGATAGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGCTCATTGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGTAGTTACGGCATTAACGCCCAGGATTTGCAAAAATGGCGTAAATCGGGAAACCGGCT
ATTCCGCTGTTTCGTCAACGTGAGCAGAGCTAACCCGGTTAGCCTTTCCTGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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