Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 312887..313467 Replicon plasmid p2
Accession NZ_CP071606
Organism Rhizobium binae strain BLR195

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J2J99_RS26010 Protein ID WP_168302163.1
Coordinates 312887..313270 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J2J99_RS26015 Protein ID WP_168302162.1
Coordinates 313267..313467 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J2J99_RS25985 308257..308847 + 591 WP_168302168.1 hypothetical protein -
J2J99_RS25990 308879..309454 + 576 WP_168302167.1 hypothetical protein -
J2J99_RS25995 310070..310504 - 435 WP_168302166.1 redox-sensitive transcriptional activator SoxR -
J2J99_RS26000 310590..311312 + 723 WP_168302165.1 SDR family NAD(P)-dependent oxidoreductase -
J2J99_RS26005 311309..312370 + 1062 WP_168302164.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
J2J99_RS26010 312887..313270 - 384 WP_168302163.1 type II toxin-antitoxin system VapC family toxin Toxin
J2J99_RS26015 313267..313467 - 201 WP_168302162.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
J2J99_RS26020 314489..315406 - 918 WP_207600984.1 zinc-binding dehydrogenase -
J2J99_RS26025 315682..315984 + 303 Protein_322 hypothetical protein -
J2J99_RS26030 316114..318267 + 2154 WP_168302395.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..498121 498121


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14225.40 Da        Isoelectric Point: 7.1865

>T196607 WP_168302163.1 NZ_CP071606:c313270-312887 [Rhizobium binae]
VILADTSIWIDHFRHVDAELRTIIQDDLLLCHPAVVGELALGSLRDRERVITFLAAQRQAFVATHDEVMTMIDRHGIFSM
GIGYTDAHLLASILLDRRAALWTRDKRLQAAAEKAGASLHKPAHPRN

Download         Length: 384 bp

>T196607 NZ_CP095178:131029-131511 [Enterobacter hormaechei]
GTGGGACGTATAACCACGCCCGAGCCGTTATCCAGCTCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGTAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTCCACGATGCAGTGCTACGGTGTTATCGCGTAGCTGAGAACATTGGGGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7138.26 Da        Isoelectric Point: 11.3760

>AT196607 WP_168302162.1 NZ_CP071606:c313467-313267 [Rhizobium binae]
MRSTINLDDTLMERAKSLTGTKETAALVRQALETLIRVESGRRLIALGGTMPDAEAAPRRRSAAAK

Download         Length: 201 bp

>AT196607 NZ_CP095178:130775-131041 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCTGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References