Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1819243..1820019 Replicon chromosome
Accession NZ_CP071589
Organism Staphylococcus simiae strain 17941E

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag J3R86_RS08225 Protein ID WP_207516908.1
Coordinates 1819243..1819398 (-) Length 52 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag J3R86_RS08230 Protein ID WP_207516909.1
Coordinates 1819420..1820019 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3R86_RS08205 1814550..1815671 - 1122 WP_207518538.1 GAF domain-containing protein -
J3R86_RS08210 1815830..1816651 + 822 WP_207516905.1 RluA family pseudouridine synthase -
J3R86_RS08215 1817122..1818507 - 1386 WP_207516906.1 class II fumarate hydratase -
J3R86_RS08220 1818690..1819091 - 402 WP_207516907.1 hypothetical protein -
J3R86_RS08225 1819243..1819398 - 156 WP_207516908.1 hypothetical protein Toxin
J3R86_RS08230 1819420..1820019 - 600 WP_207516909.1 glucosamine-6-phosphate isomerase Antitoxin
J3R86_RS08235 1820309..1820779 - 471 WP_207516910.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
J3R86_RS08240 1820781..1821911 - 1131 WP_207516911.1 tRNA epoxyqueuosine(34) reductase QueG -
J3R86_RS08245 1822056..1822778 - 723 WP_207516912.1 ATP-binding cassette domain-containing protein -
J3R86_RS08250 1822771..1824228 - 1458 WP_207516913.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(126-196)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 6063.39 Da        Isoelectric Point: 4.0406

>T196574 WP_207516908.1 NZ_CP071589:c1819398-1819243 [Staphylococcus simiae]
MVNEKDAKLNYHEDENAMVNDFDDLKELGKEMEQISEENDQEKHNQSHDNN

Download         Length: 156 bp

>T196574 NZ_CP095164:137066-137416 [Edwardsiella anguillarum]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22616.61 Da        Isoelectric Point: 4.8524

>AT196574 WP_207516909.1 NZ_CP071589:c1820019-1819420 [Staphylococcus simiae]
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNVDHHAVDFSQINILDYDNNQSYFEALGV
PKSQIYAIEFEKDAIEFISDKIKTKENKGKLTLQVLSISEQGHLDVSVRQGLMEAREIILVITGVNKREMVEKLYQENGK
SSYEPADLKAHRMVNVILDKEAAEGLPEDVKTYFTSRFA

Download         Length: 600 bp

>AT196574 NZ_CP095164:137421-137723 [Edwardsiella anguillarum]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References