196570

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 5358728..5359403 Replicon chromosome
Accession NZ_CP071586
Organism Pseudomonas germanica strain FIT28

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag J0G10_RS23730 Protein ID WP_095048139.1
Coordinates 5358728..5359096 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag J0G10_RS23735 Protein ID WP_095048140.1
Coordinates 5359083..5359403 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0G10_RS23705 (J0G10_23725) 5354507..5355697 - 1191 WP_095048134.1 hypothetical protein -
J0G10_RS23710 (J0G10_23730) 5355783..5356502 - 720 WP_095048135.1 hypothetical protein -
J0G10_RS23715 (J0G10_23735) 5356579..5357394 - 816 WP_220556866.1 sulfite exporter TauE/SafE family protein -
J0G10_RS23720 (J0G10_23740) 5357507..5358274 + 768 WP_095126163.1 helix-turn-helix transcriptional regulator -
J0G10_RS23725 (J0G10_23745) 5358368..5358685 + 318 WP_095126164.1 hypothetical protein -
J0G10_RS23730 (J0G10_23750) 5358728..5359096 + 369 WP_095048139.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J0G10_RS23735 (J0G10_23755) 5359083..5359403 + 321 WP_095048140.1 helix-turn-helix transcriptional regulator Antitoxin
J0G10_RS23740 (J0G10_23760) 5359415..5360470 - 1056 WP_095048141.1 MBL fold metallo-hydrolase -
J0G10_RS23745 (J0G10_23765) 5360687..5361295 + 609 WP_095048142.1 TetR/AcrR family transcriptional regulator -
J0G10_RS23750 (J0G10_23770) 5361452..5362519 + 1068 WP_220558892.1 diguanylate cyclase -
J0G10_RS23755 (J0G10_23775) 5362710..5364029 + 1320 WP_220556867.1 PAS domain-containing methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13585.55 Da        Isoelectric Point: 9.7417

>T196570 WP_095048139.1 NZ_CP071586:5358728-5359096 [Pseudomonas germanica]
MSARKPLLWVCSSKKDLKQMPTDVQDVFGYALDLAQIGLKHPDAKPLKGFGGAGVLELIENFDTNTYRAIYTVRFGSAIY
VLHCFQKKSTTGIKTAQSDVDLIRNRLRAAQDHAKGSENDRN

Download         Length: 369 bp

>T196570 NZ_CP095163:1212321-1212524 [Edwardsiella anguillarum]
ATGACCAAGATCGATTATCTAATGAAGCTGCGTAAATGCACGACGCTGGATACTCTGGAACGCGTGATCGAAAAGAATAA
ATACGAACTTTCAGATGATGAACTAGAAATTTTTTATTCTGCTGCAGATCATCGACTAGCCGAATTAACTATGAATAAGC
TATACGACAAAATTCCGGCAGAAGTCTGGCAATACGTCCGCTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11776.78 Da        Isoelectric Point: 9.7510

>AT196570 WP_095048140.1 NZ_CP071586:5359083-5359403 [Pseudomonas germanica]
MIEIEKGSGNVYQDLELPNASEMQVKSQLAAKIGEIIKARHLTQIQASEILGLSQPKLSEMLRGKFRGISEAKMMECLSH
LGRDVQIVVKSAPRSRKEGRIEVVFA

Download         Length: 321 bp

>AT196570 NZ_CP095163:1211932-1212300 [Edwardsiella anguillarum]
ATGGATGAGTATACTTCTTATCAGCATGACATCGCAGAGTTAAAATACCTGTGTGATTCTCTGTATCATCAGGGAATAGA
TGTCCTGGGAGAGAGCCATCACGGCTGGGTCAGCGACCCGACGGCAAAGGTAAACCTACAGCTTAACGAGCTGATTGAGC
ATATTGCCAGCGTCGCACAATCATTTAAGATCAAATATCCGCGTCATTCGGATTTAGCCGAAATACTGGATGATTATCTG
GATGAAACCTACGCCCTGTTTGGTGCCTATAGCGTCAGTGAAACGGCGCTCAGACACTGGCTGCGTACCAAACGCCGTGT
GGCATACTGCCTGGCGCATGAAAAGCGCAATGCGGCCTTACATGTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References